Exploring the Potent Inhibition of CTP Synthase by Gemcitabine-5′-Triphosphate-Reference-Cited by-同舟云学术

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Exploring the Potent Inhibition of CTP Synthase by Gemcitabine-5′-Triphosphate

Published:2016-11-16 Issue:23 Volume:17 Page:2240-2249
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

McCluskey Gregory D.¹,Mohamady Samy²,Taylor Scott D.³,Bearne Stephen L.¹⁴

Affiliation:

1. Department of Biochemistry and Molecular Biology; Dalhousie University; Halifax Nova Scotia B3H 4R2 Canada

2. Faculty of Pharmacy; The British University in Egypt; 11837 Cairo Egypt

3. Department of Chemistry; University of Waterloo; Waterloo Ontario N2L 3G1 Canada

4. Department of Chemistry; Dalhousie University; Halifax Nova Scotia B3H 4R2 Canada

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Reference91 articles.

1. [36] CTP synthetase

2. Role of antimetabolites of purine and pyrimidine nucleotide metabolism in tumor cell differentiation

3. Metabolic and molecular aspects of ethanolamine phospholipid biosynthesis: the role of CTP:phosphoethanolamine cytidylyltransferase (Pcyt2)

4. Effect of CTP Synthetase Regulation by CTP on Phospholipid Synthesis in Saccharomyces cerevisiae

5. CMP-N-Acetylneuraminic Acid Synthetase from Escherichia coli K1 Is a Bifunctional Enzyme

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4. A metal‐dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine‐5′‐triphosphate;Protein Science;2023-05-13

5. Effects of the 5′‐Triphosphate Metabolites of Ribavirin, Sofosbuvir, Vidarabine, and Molnupiravir on CTP Synthase Catalysis and Filament Formation: Implications for Repurposing Antiviral Agents against SARS‐CoV‐2;ChemMedChem;2022-10-26

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