An Integrated Computational and Experimental Approach to Gaining Selectivity for MMP-2 within the Gelatinase Subfamily-Reference-Cited by-同舟云学术

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An Integrated Computational and Experimental Approach to Gaining Selectivity for MMP-2 within the Gelatinase Subfamily

Published:2014-01-21 Issue:3 Volume:15 Page:399-412
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Fabre Benjamin,Filipiak Kamila,Díaz Natalia,Zapico José María,Suárez Dimas,Ramos Ana,de Pascual-Teresa Beatriz

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cbic.201300698/fullpdf

Reference59 articles.

1. How Matrix Metalloproteinases Regulate Cell Behavior

2. http://degradome.uniovi.es/ http://merops.sanger.ac.uk/

3. Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy

4. Quest for Selectivity in Inhibition of Matrix Metalloproteinases

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1. Influence of N-arylsulfonamido d-valine N-substituents on the selectivity and potency of matrix metalloproteinase inhibitors;Bioorganic & Medicinal Chemistry;2023-07

2. Selective Inhibitors of Medium-Size S1′ Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery;Journal of Medicinal Chemistry;2022-08-15

3. Discovery of Aryloxyphenyl–Heptapeptide Hybrids as Potent and Selective Matrix Metalloproteinase-2 Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis;Journal of Medicinal Chemistry;2022-06-10

4. Design and Synthesis of Water-Soluble and Potent MMP-13 Inhibitors with Activity in Human Osteosarcoma Cells;International Journal of Molecular Sciences;2021-09-15

5. Understanding the variability of the S1′ pocket to improve matrix metalloproteinase inhibitor selectivity profiles;Drug Discovery Today;2020-01

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