Development of Chitosan/Mg−Zn−HAP/ZrO2 Bilayer Coating on Ti Alloy for Biomedical Applications

Abstract

AbstractTitanium alloys (Ti−6Al−4V) are being used in many biomedical applications due to their unique properties of bioactivity, excellent mechanical properties, low toxicity, biocompatibility, and long‐term implant application for their satisfactory corrosion resistance. We have developed a new two‐step fabrication process of zirconium oxide (ZrO2) and Chitosan/Mg−Zn−HAP (Chitosan/M−HAP) bilayer layer coating on Ti alloy for biomedical applications. Flower‐structured bilayers were coated by the electrochemical deposition method. Electrochemically deposited bilayer‐coated Ti alloy specimens were characterized by various analytical techniques like field‐emission scanning electron microscope (FE‐SEM), X‐ray diffraction (XRD), and EDS mapping analysis. Furthermore, the developed bilayer (Chitosan/Mg−Zn−HAP/ZrO2) coated Ti alloy samples improved mechanical properties such as adhesion strength (20.1±0.4 MPa) and hardness (446±4 Hv), compared to other coatings. An investigation of polarization curves showed a positive shift in the polarization values (Ecorr, and Icorr) of the Chitosan/M−HAP/ZrO2 bilayer coatings on Ti alloy. Bilayer‐modified Ti alloy samples show good antimicrobial response toward Gram‐negative and Gram‐positive bacteria. Meanwhile, the cell viability and proliferation of the bilayer‐coated samples were evaluated and the exhibited result improved cell proliferation, and bioactivity compared to other coated materials. From the results, it can be evident that the developed Chitosan/Mg−Zn−HAP/ZrO2 bilayer‐coated Ti alloy could be a good potential candidate for biomedical applications.