Transition‐Metal Catalyzed Coupling Reactions for the Synthesis of (Het)aryl Ketones: An Approach from their Synthesis to Biological Perspectives

Author:

Karakaya Idris1ORCID,Rizwan Komal2,Munir Shahid3

Affiliation:

1. Department of Chemistry College of Basic Sciences Gebze Technical University 41400 Gebze Turkey

2. Department of Chemistry University of Sahiwal Sahiwal 57000 Pakistan

3. Institute of Energy and Environmental Engineering University of the Punjab Lahore 54590 Pakistan

Abstract

AbstractSynthetic protocols capable of incorporating acyl based functional moieties have been proved fruitful to develop variety of carbonyl containing organic molecules. Substituted‐aromatic ketones are important motifs in different natural products and biologically active pharmaceuticals. Substituted aromatic ketones based compounds have been proved effective as antioxidant, antiallergic, antimicrobial, antimitotic, anticholinergic, antiinflammatory, anticonvulsant, antipsychotic age, anticancer, antimicrobial, antimalarial, and antiviral agents, Transition metals are necessary part of modern catalytic systems for carbonylative transformations. Carbonylative coupling reaction involves direct introduction of carbonyl fragment for synthesis of biaryls, aryl/alkyl ketones through transition metals based catalytic systems. In this review, we have reported the synthesis of biaryls, aryl/alkyl ketones by using different feed stocks in presence of various transition metal catalysts.

Publisher

Wiley

Subject

General Chemistry

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3