Affiliation:
1. Department Pharmaceutical organic chemistry Institution Faculty of Pharmacy Cairo University Address 1, 33 Kasr El-Aini street Cairo Egypt
2. Department Pharmaceutical Analytical chemistry Institution Faculty of Pharmacy Cairo University Address 1, 33 Kasr El-Aini street Cairo Egypt
Abstract
Abstractβ‐Carboline ring is widely distributed in nature and several β‐carboline alkaloids were extracted from marine creatures, bacteria, fungi, food stuffs, plants, and mammals. Synthetic β‐carbolines derivatives were reported to exhibit various biological activities. This review highlighted the recent progress achieved in the last decade in the Pictet‐Spengler synthesis of β‐carboline derivatives with a special focus on the green methods and green catalysts used for the synthesis.