Affiliation:
1. School of Pharmacy Nantong University 19 Qixiu Road Nantong Jiangsu Province 226001 China.
Abstract
Abstract2‐Acylindoles possess widespread applications in functional chemicals. However, the convenient and selective synthesis of such important substructures has to date remained a challenge. Herein, a method to achieve 2‐acylindoles from sulfoxonium ylides with o‐aminoaryl aldehydes catalysed by Iridium has been developed with the merits of broad substrate scope, good functional tolerance, high efficiency and operational simplicity, which provides an alternative way to access functionalized indoles.
Funder
National Natural Science Foundation of China