Affiliation:
1. Department of Chemistry University of Swabi Swabi Pakistan
2. Department of Chemistry, College of Science Princess Nourah bint Abdulrahman University Riyadh Saudi Arabia
3. Operations and Method Development Shefali Research Laboratories Ambernath India
4. Department of Medical Laboratory Technology, College of Applied Medical Sciences Taibah University Al Madinah Al Munawwarah Saudi Arabia
5. Department of Medical Biochemistry Abubakar Tafawa Balewa University Bauchi Nigeria
6. Department of Biotechnology Bacha Khan University Khyber Pakhtunkhwa Pakistan
7. Center of Biotechnology and Microbiology University of Peshawar Peshawar Pakistan
8. Nutrition and Bromatology Group, Analytical Chemistry and Food Science Department, Faculty of Science Universidade de Vigo Ourense Spain
Abstract
AbstractEdible mushrooms are popular functional foods attributed to their rich nutritional bioactive constituent profile influencing cardiovascular function. Edible mushrooms are omnipresent in various prescribed Dietary Approaches to Stop Hypertension, Mediterranean diet, and fortified meal plans as they are rich in amino acids, dietary fiber, proteins, sterols, vitamins, and minerals. However, without an understanding of the influence of mushroom bioactive constituents, mechanism of action on heart and allergenicity, it is difficult to fully comprehend the role of mushrooms as dietary interventions in alleviating hypertension and other cardiovascular malfunctions. To accomplish this endeavor, we chose to review edible mushrooms and their bioactive constituents in ameliorating hypertension. Hypertension and cardiovascular diseases are interrelated and if the former is managed by dietary changes, it is postulated that overall heart health could also be improved. With a concise note on different edible varieties of mushrooms, a particular focus is presented on the antihypertensive potential of mushroom bioactive constituents, mode of action, absorption kinetics and bioavailability. Ergosterol, lovastatin, cordycepin, tocopherols, chitosan, ergothioneine, γ‐aminobutyric acid, quercetin, and eritadenine are described as essential bioactives with hypotensive effects. Finally, safety concerns on allergens and limitations of consuming edible mushrooms with special reference to chemical toxins and their postulated metabolites are highlighted. It is opined that the present review will redirect toxicologists to further investigate mushroom bioactives and allergens, thereby influencing dietary interventions for heart health.
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献