Congenital small bowel obstruction: Prenatal detection and outcome

Author:

Heinrich H.12ORCID,Pijpers A. G. H.3,Linskens I. H.24,van Leeuwen E.12,Schattenkerk L. D. Eeftinck3,Derikx J. P. M.3,Pajkrt E.12

Affiliation:

1. Department of Obstetrics and Gynecology Amsterdam UMC, Location University of Amsterdam Amsterdam the Netherlands

2. Amsterdam Reproduction and Development Amsterdam the Netherlands

3. Department of Pediatric Surgery Amsterdam UMC, Location University of Amsterdam Amsterdam the Netherlands

4. Department of Obstetrics and Gynecology Amsterdam UMC, Location Vrije Universiteit Amsterdam Amsterdam the Netherlands

Abstract

AbstractObjectiveTo evaluate and compare the outcome of fetuses and neonates with congenital small bowel obstructions (SBO), evaluate the screening performance of prenatal ultrasound for SBO and identify possible risk factors for adverse outcomes.MethodsAll cases referred to the Amsterdam University Medical Centers between 2007 and 2021 for a prenatal suspected SBO, supplemented by cases of postnatal diagnosis of SBO, were included. The primary outcome was survival after 24 weeks of gestation until the first year of life.Results147 cases of SBO were included with a survival rate of 86.2% (119/138) after 24 weeks of gestation until the first year of age. Additional structural or chromosomal anomalies were found to have an increased risk of adverse outcomes. Intrauterine fetal demise occurred in 10/147 (6.8%) cases and 9/147 (6.1%) cases died during postnatal follow‐up. The overall positive predictive value of all prenatally diagnosed cases was 91.5%. Surgical correction was performed in 123/128 (96.0%) of the live‐born cases.ConclusionsCongenital SBO has an overall favorable prognosis, but the outcome is negatively impacted by the possible presence of additional structural or chromosomal anomalies. Fetal monitoring in the early third trimester should be considered, since all cases of Intrauterine fetal demise occurred between 30 and 35 weeks of gestation.

Publisher

Wiley

Subject

Genetics (clinical),Obstetrics and Gynecology

Reference35 articles.

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2. Small intestinal atresia in a defined population: occurrence, prenatal diagnosis and survival

3. Congenital atresia of the intestine: pathogenesis and treatment;Santulli TV;Ann Surg,1961

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