Affiliation:
1. Beijing National Laboratory for Molecular Sciences (BNLMS) CAS Key Laboratory of Molecular Recognition and Function CAS Research/Education Center for Excellence in Molecular Sciences Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China
2. University of Chinese Academy of Sciences Beijing 100049 China
Abstract
AbstractThe widespread involvement of 5‐formylcytosine f5C RNA in gene function regulation and its impact on crucial life processes like cell differentiation, embryonic development, and disease development underscores the significance of detecting this specific base modification. This detection holds great importance for basic epigenetics research and the early diagnosis and pathogenesis research of various diseases. This review aims to summarize recent research progress in f5C detection methods using selective chemical labeling, with the hope of aiding future research endeavors.
Funder
National Natural Science Foundation of China
Chinese Academy of Sciences
Cited by
2 articles.
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