Targeting the CD80/CD86 costimulatory pathway with CTLA4-Ig directs microglia toward a repair phenotype and promotes axonal outgrowth
Author:
Affiliation:
1. INSERM UMR 1064, ITUN, CHU Nantes, University of Nantes; France
2. INSERM UMR 913, IMAD, University of Nantes; France
Funder
INSERM, Fondation Progreffe, and the Region Pays de la Loire (to A.N.)
Publisher
Wiley
Subject
Cellular and Molecular Neuroscience,Neurology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/glia.22894/fullpdf
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3. CD28-B7 T cell costimulatory blockade by CTLA4Ig in the rat renal allograft model: Inhibition of cell-mediated and humoral immune responses in vivo;Akalin;Transplantation,1996
4. Relative efficiency of microglia, astrocytes, dendritic cells and B cells in naive CD4+ T cell priming and Th1/Th2 cell restimulation;Aloisi;Eur J Immunol,1999
5. Inhibition of brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor expression reduces dopaminergic sprouting in the injured striatum;Batchelor;Eur J Neurosci,2000
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