Developing and validating a multivariable prediction model to improve the diagnostic accuracy in determination of cervical versus endometrial origin of uterine adenocarcinomas: A prospective MR study combining diffusion-weighted imaging and spectroscopy

Author:

Lin Gigin123ORCID,Lin Yu-Chun12,Wu Ren-Chin4,Yang Lan-Yan56,Lu Hsin-Ying123,Tsai Shang-Yueh7,Huang Yu-Ting8,Huang Yen-Ling1,Lu Kuan-Ying123,Ng Koon-Kwan8,Yen Tzu-Chen9,Chao Angel56,Lai Chyong-Huey56,Hong Ji-Hong210

Affiliation:

1. Department of Medical Imaging and Intervention; Chang Gung Memorial Hospital at LinkouGuishan; Taoyuan Taiwan

2. Imaging Core Laboratory, Institute for Radiological Research, Chang Gung Memorial Hospital at Linkou and Chang Gung University; Guishan Taoyuan Taiwan

3. Clinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou; Guishan Taoyuan Taiwan

4. Department of Pathology; Chang Gung Memorial Hospital at Linkou and Chang Gung University; Guishan Taoyuan Taiwan

5. Department of Obstetrics and Gynecology and Gynecologic Cancer Research Center; Chang Gung Memorial Hospital at Linkou and Chang Gung University; Guishan Taoyuan Taiwan

6. Clinical Trial Center, Chang Gung Memorial Hospital at Linkou and Chang Gung University; Guishan Taoyuan Taiwan

7. Graduate Institute of Applied Physics; National Chengchi University; Taipei Taiwan

8. Department of Diagnostic Radiology; Chang Gung Memorial Hospital at Keelung; Keelung Taiwan

9. Department of Nuclear Medicine and Center for Advanced Molecular Imaging and Translation; Chang Gung Memorial Hospital and Chang Gung University, Linkou Medical Center; Guishan Taoyuan Taiwan

10. Department of Radiation Oncology; Chang Gung Memorial Hospital at Linkou and Chang Gung University; Guishan Taoyuan Taiwan

Funder

Cancer Center and the Clinical Trial Center

Chang Gung Memorial Hospital, Linkou, Taiwan

Chang Gung Medical Foundation

National Science Council (Taiwan)

Ministry of Health and Welfare of Taiwan

Publisher

Wiley

Subject

Radiology Nuclear Medicine and imaging

Reference29 articles.

1. Cancer statistics, 2017;Siegel;CA Cancer J Clin,2017

2. NCCN Clinical Practice Guidelines in Oncology Uterine Cancers http://www.nccn.org/professionals/physician_gls/pdf/uterine.pdf

3. ACOG practice bulletin, clinical management guidelines for obstetrician-gynecologists, number 65, August 2005: management of endometrial cancer;American College of O, Gynecologists;Obstet Gynecol,2005

4. Progesterone receptor does not improve the performance and test effectiveness of the conventional 3-marker panel, consisting of estrogen receptor, vimentin and carcinoembryonic antigen in distinguishing between primary endocervical and endometrial adenocarcinomas in a tissue microarray extension study;Liao;J Transl Med,2009

5. A panel of immunohistochemical stains, including carcinoembryonic antigen, vimentin, and estrogen receptor, aids the distinction between primary endometrial and endocervical adenocarcinomas;McCluggage;Int J Gynecol Pathol,2002

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