A mechanistic model to account for the Donnan and volume exclusion effects in ultrafiltration/diafiltration process of protein formulations
Author:
Affiliation:
1. Bioproduct Research and Development Lilly Research Laboratories, Eli Lilly and Company Indianapolis Indiana USA
Publisher
Wiley
Subject
Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/btpr.3106
Reference25 articles.
1. Effect of protein and solution properties on the Donnan effect during the ultrafiltration of proteins;Bolton GR;Biotechnol Prog,2010
2. A Small-Scale Process for Predicting Donnan and Volume Exclusion Effects During Ultrafiltration/Diafiltration Process Development
3. Viscosity of concentrated therapeutic protein compositions
4. Subcutaneous Injection of Drugs: Literature Review of Factors Influencing Pain Sensation at the Injection Site
5. Protein−solute interactions affect the outcome of ultrafiltration/diafiltration operations
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