A preparation pulse for fast steady state approach in Actual Flip angle Imaging

Author:

Zampini Marco Andrea12,Sijbers Jan34,Verhoye Marleen24,Garipov Ruslan1

Affiliation:

1. MR Solutions Ltd. Ashbourne House Guildford Surrey UK

2. Bio‐Imaging Lab Department of Biomedical Sciences University of Antwerp Belgium

3. imec‐Vision Lab, Department of Physics University of Antwerp Belgium

4. μNEURO Research Centre of Excellence University of Antwerp Belgium

Abstract

AbstractBackgroundActual Flip angle Imaging (AFI) is a sequence used for B1 mapping, also embedded in the Variable flip angle with AFI for simultaneous estimation of T1, B1 and equilibrium magnetization.PurposeTo investigate the design of a preparation module for AFI to allow a fast approach to steady state (SS) without requiring the use of dummy acquisitions.MethodsThe features of a preparation module with a B1 insensitive adiabatic pulse, spoiler gradients, and a recovery time were studied with simulations and validated via experiments and acquired with different k‐space traveling strategies. The robustness of the flip angle of the preparation pulse on the acquired signal is studied.ResultsWhen a 90° adiabatic pulse is used, the forthcoming can be expressed as a function of repetition times and AFI flip angle only as , where n represents the ratio between the two repetition times of AFI. The robustness of the method is demonstrated by showing that using the values further away from 90° still allows for a faster approach to SS than the use of dummy pulses.ConclusionsThe preparation module is particularly advantageous for low flip angles, as well as for AFI sequences that sample the center of the k‐space early in the sequence, such as centric ordering acquisitions, and for ultrafast EPI‐based AFI methods, thus allowing to reduce scanner overhead time.

Funder

H2020 European Institute of Innovation and Technology

Publisher

Wiley

Subject

General Medicine

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