Sympathetic Neurostress Drives Osteoblastic Exosomal MiR‐21 Transfer to Disrupt Bone Homeostasis and Promote Osteopenia

Author:

Hu Cheng‐Hu12,Sui Bing‐Dong1,Liu Jin3,Dang Lei3,Chen Ji1,Zheng Chen‐Xi1,Shi Songtao4,Zhao Na5,Dang Min‐Yan16,He Xiao‐Ning16,Zhang Li‐Qiang16,Gao Ping‐Ping16,Chen Nan1,Kuang Hui‐Juan56,Chen Kai1,Xu Xiao‐Lin6,Yu Xiao‐Rui2,Zhang Ge3,Jin Yan16ORCID

Affiliation:

1. State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi International Joint Research Center for Oral Diseases Center for Tissue Engineering School of Stomatology The Fourth Military Medical University Xi'an Shaanxi 710032 China

2. Department of Biochemistry and Molecular Biology School of Basic Medical Sciences Xi'an Jiaotong University Xi'an Shaanxi 710032 China

3. Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases School of Chinese Medicine Hong Kong Baptist University Hong Kong SAR 999077 China

4. South China Center of Craniofacial Stem Cell Research Sun Yat‐sen University, Guangzhou Guangdong 510080 China

5. Institute for Stem Cell and Regenerative Medicine The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an Shaanxi 710032 China

6. Xi'an Institute of Tissue Engineering and Regenerative Medicine Xi'an Shaanxi 710032 China

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Materials Science,General Chemistry

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