A New Option for Glycemic Control: Insulin Degludec, a New‐Generation Basal Insulin with an Ultralong Duration of Action
Author:
Affiliation:
1. University of Pittsburgh School of Pharmacy Pittsburgh Pennsylvania
2. University Diabetes Care Associates Pittsburgh Pennsylvania
3. Scripps Whittier Diabetes Institute‐Scripps Health La Jolla California
Publisher
Wiley
Subject
Pharmacology (medical)
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/phar.1361
Reference57 articles.
1. Design of the Novel Protraction Mechanism of Insulin Degludec, an Ultra-long-Acting Basal Insulin
2. Insulin preparations with prolonged effect;Owens DR;DiabTechnol Ther,2011
3. Insulin degludec has a two‐fold longer half‐life and a more consistent pharmacokinetic profile than insulin glargine;Heise T;Diabetes,2011
4. Ultra‐long‐acting insulin degludec has a flat and stable glucose‐lowering effect in type 2 diabetes
5. Steady state is reached within two to three days of once‐daily administration of ultra‐long‐acting insulin degludec;Heise T;Diabetes,2012
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3. Clinically Relevant Insulin Degludec and Its Interaction with Polysaccharides: A Biophysical Examination;Polymers;2020-02-09
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5. Stapled, Long-Acting Glucagon-like Peptide 2 Analog with Efficacy in Dextran Sodium Sulfate Induced Mouse Colitis Models;Journal of Medicinal Chemistry;2018-03-12
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