Enzymatic Late‐Stage Oxidation of Lead Compounds with Solubilizing Biomimetic Docking/Protecting groups-Reference-Cited by-同舟云学术

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Enzymatic Late‐Stage Oxidation of Lead Compounds with Solubilizing Biomimetic Docking/Protecting groups

Published:2018-11-19 Issue:68 Volume:24 Page:17936-17947
ISSN:0947-6539
Container-title:Chemistry – A European Journal
language:en
Short-container-title:Chem. Eur. J.

Author:

Vickers Clare¹^ORCID,Backfisch Gisela²^ORCID,Oellien Frank¹^ORCID,Piel Isabel¹^ORCID,Lange Udo E. W.¹^ORCID

Affiliation:

1. Neuroscience Discovery, Medicinal ChemistryAbbVie (Deutschland) GmbH & Co. KG Knollstrasse D-67061 Ludwigshafen Germany

2. Development Sciences, DMPK and Bioanalytical ResearchAbbVie (Deutschland) GmbH & Co. KG Knollstrasse D-67061 Ludwigshafen Germany

Funder

AbbVie Deutschland

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/chem.201802331

Reference100 articles.

1.

2. Emerging technologies for metabolite generation and structural diversification

3. Biocatalysis at Work: Applications in the Development of Sagopilone

4. Chemo-enzymatic fluorination of unactivated organic compounds

5. Combination of biotransformation by P450 BM3 mutants with on-line post-column bioaffinity and mass spectrometric profiling as a novel strategy to diversify and characterize p38α kinase inhibitors

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