Effect of Food Intake on the Pharmacodynamics of Tenapanor: A Phase 1 Study
Author:
Affiliation:
1. AstraZeneca Gothenburg; Mölndal Sweden
2. Ardelyx, Inc.; Fremont CA USA
Funder
AstraZeneca
Ardelyx, Inc.
Publisher
Wiley
Subject
Pharmacology (medical),Pharmaceutical Science
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/cpdd.341/fullpdf
Reference27 articles.
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3. Cloning and sequencing of a rabbit cDNA encoding an intestinal and kidney-specific Na+/H+ exchanger isoform (NHE-3);Tse;J Biol Chem,1992
4. Deciphering the mechanisms of the Na+/H+ exchanger-3 regulation in organ dysfunction;Girardi;Am J Physiol Cell Physiol,2012
5. A phase 1 study of the safety, tolerability, pharmacodynamics, and pharmacokinetics of tenapanor in healthy Japanese volunteers;Johansson;Clin Exp Nephrol
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