Central (ICV) leptin injection increases bone formation, bone mineral density, muscle mass, serum IGF-1, and the expression of osteogenic genes in leptin-deficient ob/ob mice-Reference-Cited by-同舟云学术

Central (ICV) leptin injection increases bone formation, bone mineral density, muscle mass, serum IGF-1, and the expression of osteogenic genes in leptin-deficient ob/ob mice

Published:2011-07-20 Issue:8 Volume:26 Page:1710-1720
ISSN:0884-0431
Container-title:Journal of Bone and Mineral Research
language:en
Short-container-title:J Bone Miner Res

Author:

Bartell Shoshana M,Rayalam Srujana,Ambati Suresh,Gaddam Dhanunjaya R,Hartzell Diane L,Hamrick Mark,She Jin-Xiong,Della-Fera Mary Anne,Baile Clifton A

Publisher

Wiley

Subject

Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jbmr.406/fullpdf

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3. Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes;Thomas;Endocrinology.,1999

4. Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass;Ducy;Cell.,2000

5. Leptin is expressed in and secreted from primary cultures of human osteoblasts and promotes bone mineralization;Reseland;J Bone Miner Res.,2001

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