Affiliation:
1. Interdisciplinary Research Center for Artificial Intelligence College of Materials Science and Engineering State Key Laboratory of Organic‐Inorganic Composites Beijing University of Chemical Technology Beijing 100029 China
2. College of Life Science and Technology Beijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing University of Chemical Technology Beijing 100029 China
3. Department of Pathology Peking University International Hospital Beijing 102206 China
4. School of Emergent Soft Matter South China University of Technology Guangzhou 510640 China
Abstract
AbstractConductive hydrogel‐based epidermal sensors are regarded with broad prospects in bridging the gap between human and machine for personalized healthcare. However, it is still challenging to simultaneously achieve high sensitivity, wide sensing range, and reliable cycling stability in hydrogel‐based epidermal sensors for ultrasensitive human–machine interfacing, along with brilliant antiswelling capability, and near‐infrared (NIR) light‐triggered dissociation and drug release for further smart on‐demand photothermal therapy. Herein, the facile preparation of a flexible multifunctional epidermal sensor from the elaborately fabricated, highly stretchable, and antiswelling MXene hydrogel is presented. It exhibits high sensitivity, wide sensing range (up to 350% strain), and reliable reproducibility for enabling ultrasensitive human‐machine interfacing. It displays excellent antiswelling capability for the hydrogel to avoid expanding the wound due to excessive swelling for further reliable wound therapy. Furthermore, it possesses good biocompatibility and robust photothermal performance for the smart photothermal therapy after healthcare monitoring. Meanwhile, the sensor can be triggered to be softened and partly dissociated under the prolonged NIR light irradiation with the transformation of the temperature‐sensitive low‐melting‐point Agar into a sol state and the partial dissociation in the hydrogel to release the loaded drug on demand for synergistically sterilizing bacteria and efficiently promoting wound healing.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Beijing Municipality
Fundamental Research Funds for the Central Universities
Subject
Electrochemistry,Condensed Matter Physics,Biomaterials,Electronic, Optical and Magnetic Materials
Cited by
56 articles.
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