Affiliation:
1. Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon‐Based Functional Materials and Devices Soochow University Suzhou 215123 China
2. Monash Suzhou Research Institute Monash University Suzhou 215000 China
3. Department of Materials Science and Engineering Monash University Clayton VIC 3800 Australia
4. Australian Regenerative Medicine Institute Clayton VIC 3800 Australia
5. Faculty of Civil Engineering and Mechanics Jiangsu University Zhenjiang 212013 China
6. Macao Institute of Materials Science and Engineering Macau University of Science and Technology Taipa Macau SAR 999078 China
Abstract
AbstractCancer is a serious health problem to be solved. With the development of biomaterials, enhanced diagnostic and controllable therapeutic strategies for cancer have emerged, revealing encouraging results with a promising future. Due to its outstanding tissue penetration and controllability, along with a series of bioeffects on tissues, ultrasound (US), as a common medical technology, has been regarded as an effective tool against cancer, and its use has promoted the exploration of US‐sensitive biomaterials. In this review, the bioeffects of US are first introduced and then the main US‐sensitive biomaterials (containing cavitation nuclei, sonosensitizers, and US‐responsive macromolecular systems) used to treat cancer, followed by a summary of several applications based on US‐sensitive biomaterials, from diagnosis to therapy. Finally, the emerging challenges in this field that need to be overcome are highlighted. This review reports the progress of US‐sensitive biomaterials, providing new possibilities in cancer theranostics and thus benefiting patients.
Funder
National Natural Science Foundation of China
Higher Education Discipline Innovation Project
Subject
Electrochemistry,Condensed Matter Physics,Biomaterials,Electronic, Optical and Magnetic Materials