Alzheimer's Disease: Status of Low‐Dimensional Nanotherapeutic Materials

Author:

Huang Dongqing12ORCID,Liao Wang3,Li Jun12,Chen Tongkai4,Wang Xinlu5,Zhao Ruiyue5,Zhang Lingyan6,Yu Xuefeng7,Zheng Dong8,Luan Ping12ORCID

Affiliation:

1. Department of Alzheimer's Disease Clinical Research Center Guangdong Second Provincial General Hospital Guangzhou 510317 China

2. School of Basic Medical Sciences Shenzhen University Shenzhen 518060 China

3. Department of Neurology The Second Affiliated Hospital of Guangzhou Medical University Guangzhou 510260 China

4. Science and Technology Innovation Center Guangzhou University of Chinese Medicine Guangzhou 510405 China

5. Department of Nuclear Medicine The First Affiliated Hospital of Guangzhou Medical University Guangzhou 510120 China

6. Department of Medical Imaging Longgang Central Hospital of Shenzhen Shenzhen 518116 China

7. Materials Interfaces Center Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China

8. Department of Neurology The Affiliated Brain Hospital of Guangzhou Medical University Guangzhou 510370 China

Abstract

AbstractAlzheimer's disease (AD) is a chronic progressive neurodegenerative disease that constitutes the third most common cause of death among elderly individuals. AD patients suffer from behavioral problems regularly, like memory loss, thinking deficits, and cognitive disorders. Currently, the incidence rate of AD has been on the rise worldwide. Therefore, it is imperative to develop effective strategies for the treatment and prevention of AD. The inherent characteristics of low‐dimensional nanomaterials, primarily their smaller size and surface structure, make them well‐suited for fulfilling the essential requirements of therapeutic drug design. Consequently, these nanomaterials offer a highly appealing and alternative approach to treating AD. Here, the low‐dimensional nanomaterials used in the treatment of AD to provide new ideas, methods, and comprehensive perspectives for the management of AD are reviewed. This review will advance the comprehensive understanding of the potential of low‐dimensional nanomaterials in the field of neuro medicine, which also will have a positive impact on future research.

Funder

Natural Science Foundation of Guangdong Province

National Natural Science Foundation of China

Publisher

Wiley

Subject

Electrochemistry,Condensed Matter Physics,Biomaterials,Electronic, Optical and Magnetic Materials

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