A new class of potent matrix metalloproteinase 13 inhibitors for potential treatment of osteoarthritis: Evidence of histologic and clinical efficacy without musculoskeletal toxicity in rat models-Reference-Cited by-同舟云学术

A new class of potent matrix metalloproteinase 13 inhibitors for potential treatment of osteoarthritis: Evidence of histologic and clinical efficacy without musculoskeletal toxicity in rat models

Published:2009-07 Issue:7 Volume:60 Page:2008-2018
ISSN:0004-3591
Container-title:Arthritis & Rheumatism
language:en
Short-container-title:Arthritis Rheum

Author:

Baragi Vijaykumar M.,Becher Gabriel,Bendele Alison M.,Biesinger Ralf,Bluhm Harald,Boer Jürgen,Deng Hongbo,Dodd Rory,Essers Michael,Feuerstein Tim,Gallagher Brian M.,Gege Christian,Hochgürtel Matthias,Hofmann Michael,Jaworski Andreas,Jin Lixia,Kiely Andrew,Korniski Brian,Kroth Heiko,Nix Darrell,Nolte Bert,Piecha Dorothea,Powers Timothy S.,Richter Frank,Schneider Matthias,Steeneck Christoph,Sucholeiki Irving,Taveras Arthur,Timmermann Andreas,Van Veldhuizen Joshua,Weik Juergen,Wu Xinyuan,Xia Bing

Publisher

Wiley

Subject

Pharmacology (medical),Immunology,Rheumatology,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/art.24629/fullpdf

Reference39 articles.

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3. Effect of inhibition of matrix metalloproteinases on cartilage loss in vitro and in a guinea pig model of osteoarthritis;Sabatini;Arthritis Rheum,2005

4. Ro 32-3555, an orally active collagenase selective inhibitor, prevents structural damage in the STR/ORT mouse model of osteoarthritis;Brewster;Arthritis Rheum,1998

5. Development of new hydroxamate matrix metalloproteinase inhibitors derived from functionalized 4-aminoprolines;Natchus;J Med Chem,2000

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