Affiliation:
1. Department of Neurology Xuanwu Hospital Capital Medical University Beijing China
2. Advanced Center of Stroke Beijing Institute for Brain Disorders Beijing China
3. Department of Neurology Peking University Sixth Hospital Peking University Institute of Mental Health Beijing China
4. National Clinical Research Center for Mental Disorders Peking University Sixth Hospital Beijing China
5. Department of Neurology Affiliated Hospital of Jiujiang University Jiujiang 332000 Jiangxi China
6. Department of Neurosurgery Wayne State University School of Medicine Detroit Michigan USA
7. Department of Neurosurgery Xuanwu Hospital Capital Medical University Beijing China
Abstract
AbstractObjectivesTo compare the long‐term safety and efficacy of stenting in correcting cerebral venous sinus stenosis (CVSS) and internal jugular venous stenosis (IJVS).MethodsPatients confirmed with CVSS or IJVS by imaging were enrolled in this real‐world study from 2014 through 2021. Clinical characteristics and long‐term outcomes of these two diseases entities post‐stenting were followed up and compared.ResultsThree hundred and nineteen patients were enrolled in this study, with a mean age of 48.83 years and a BMI of 25.08 on average. In which, 144 patients underwent stenting, the stenotic segments were corrected and the venous blood flow was restored immediately post‐stenting. At 6.15 ± 1.67 days follow‐up, significant improvement was observed in headache, tinnitus, insomnia, ICP, and mean pressure gradient in both groups (all p < 0.05). At 30.53 ± 4.41 months follow‐up post‐stenting, the headache, tinnitus, visual loss, papilledema, and insomnia were attenuated remarkably or even completely disappeared. The Frisen papilledema grade scores declined from 2 (0–4) to 1 (0–3) in IJVS group and from 4 (1–5) to 1 (0–4) in CVSS group compared to the baseline. One hundred and twenty‐seven out of the 144 patients (95.5%) maintained sufficient blood flow verified by followed up computed tomographic venography or contrast‐enhanced magnetic resonance angiography. Adverse events related to stenting included three cases of intraluminal restenosis and three cases of in‐stent thrombosis, no intracranial hemorrhage, venous thromboembolisms, stent‐adjacent stenosis, and stent displacement occurred.InterpretationUsing stents to correct IH and related neurological issues has shown to be a safe and effective approach for both IJVS and CVSS.
Funder
Natural Science Foundation of Beijing Municipality
National Natural Science Foundation of China
Subject
Neurology (clinical),General Neuroscience
Cited by
1 articles.
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