The application advances of dendrimers in biomedical field

Author:

Li Longjie12ORCID,Deng Yukai2,Zeng Yonghui2,Yan Bei345,Deng Yulian6,Zheng Ziyang2,Li Siqi2,Yang Yuhang2,Hao Jinwei2,Xiao Xianjin5,Wang Xinyu1

Affiliation:

1. Department of Breast Surgery Second Hospital of Jilin University Changchun China

2. Department of Biopharmaceutics, School of Life Science and Technology Wuhan Polytechnic University Wuhan China

3. Department of Human Sperm Bank Institute of Medical Sciences General Hospital of Ningxia Medical University Yinchuan China

4. Key Laboratory of Cellular Physiology (Shanxi Medical University) Ministry of Education, China Department of Physiology Shanxi Medical University Taiyuan China

5. Institute of Reproductive Health Tongji Medical College Huazhong University of Science and Technology Wuhan China

6. Department of Polymer Materials and Engineering, School of Optoelectronic Materials & Technology Jianghan University Wuhan China

Abstract

AbstractDendrimers are a family of nano‐sized three‐dimensional polymers with unique dendritic branching structures and compact spherical geometries. In recent years, dendrimers have made a series of breakthroughs in the biomedical field. In this review, we introduce the synthesis principles, modification methods, and new materials designed based on dendrimers; discuss the importance of cytotoxicity of dendrimers for applications; and elaborate on their applications in the field of molecular assembly and cancer diagnosis and treatment. We speculate that in the near future, more new materials based on dendrimers will be applied in the biomedical field.

Publisher

Wiley

Subject

Biomedical Engineering,Biomaterials

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