CYP3A4, CYP3A5, and MDR1 in Human Small and Large Intestinal Cell Llines Suitable for Drug Transport Studies

Author:

Engman Helena A.,Lennernäs Hans,Taipalensuu Jan,Otter Charlotta,Leidvik Brith,Artursson Per

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference53 articles.

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3. Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine;Wu;Clin Pharmacol Ther,1995

4. CYP3A-like cytochrome P450-mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells: Interaction between the two biochemical barriers to intestinal transport;Gan;Drug Metab Dispos,1996

5. Overlapping substrate specificities and tissue distribution of cytochrome P-450 3A and P-glycoprotein have implications for drug delivery and activity in cancer chemotherapy;Wacher;Mol Carcinog,1995

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