The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb-mTORC1 signalling and leads to chronic heart failure-Reference-Cited by-全球学者库

The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb-mTORC1 signalling and leads to chronic heart failure

Published:2015-01-07 Issue:5 Volume:235 Page:672-685
ISSN:0022-3417
Container-title:The Journal of Pathology
language:en
Short-container-title:J. Pathol.

Author:

Xu Na¹,Guan Shan²,Chen Zhong¹,Yu Yang³,Xie Jun⁴,Pan Fei-Yan²,Zhao Ning-Wei⁵,Liu Li⁶,Yang Zhong-Zhou¹,Gao Xiang¹,Xu Biao⁴,Li Chao-Jun¹

Affiliation:

1. Ministry of Education Key Laboratory of Model Animals for Disease Study; Model Animal Research Centre and Medical School of Nanjing University, National Resource Centre for Mutant Mice; Nanjing People's Republic of China

2. Jiangsu Key Laboratory for Molecular and Medical Biotechnology; College of Life Science, Nanjing Normal University; Nanjing People's Republic of China

3. State Key Laboratory of Reproductive Biology; Institute of Zoology/Chinese Academy of Sciences; Beijing People's Republic of China

4. Department of Cardiology; Affiliated Drum Tower Hospital of Nanjing University Medical School; Nanjing People's Republic of China

5. Biomedical Research Laboratory; Shimadzu (China) Co. Ltd; Shanghai People's Republic of China

6. Department of Geriatrics; First Affiliated Hospital with Nanjing Medical University; Nanjing People's Republic of China

Funder

Chinese National Programme on Key Basic Research

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/path.4480/fullpdf

Reference52 articles.

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2. Cardiac-specific overexpression of Rhoa results in sinus and atrioventricular nodal dysfunction and contractile failure;Sah;J Clin Invest,1999

3. Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1;Sussman;J Clin Invest,2000

4. Ventricular expression of a MLC-2v-ras fusion gene induces cardiac hypertrophy and selective diastolic dysfunction in transgenic mice;Hunter;J Biol Chem,1995

5. Rheb activates protein synthesis and growth in adult rat ventricular cardiomyocytes;Wang;J Mol Cell Cardiol,2008

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