Antimetastatic potentials of salvianolic acid A on oral squamous cell carcinoma by targeting MMP-2 and the c-Raf/MEK/ERK pathway

Author:

Fang Chih-Yuan12,Wu Ching-Zong134,Chen Pei-Ni56,Chang Yu-Chao78,Chuang Chun-Yi910,Lai Chih-Ting11,Yang Shun-Fa611ORCID,Tsai Lo-Lin21

Affiliation:

1. School of Dentistry; College of Oral Medicine, Taipei Medical University; Taipei Taiwan

2. Division of Oral and Maxillofacial Surgery, Department of Dentistry, Wan Fang Hospital; Taipei Medical University; Taipei Taiwan

3. Department of Dentistry; Taipei Medical University Hospital; Taipei Taiwan

4. Department of Dentistry; Lotung PohAi Hospital; Yilan Taiwan

5. Institute of Biochemistry, Microbiology and Immunology, Chung Shan Medical University; Taichung Taiwan

6. Department of Medical Research; Chung Shan Medical University Hospital; Taichung Taiwan

7. School of Dentistry; Chung Shan Medical University; Taichung Taiwan

8. Department of Dentistry; Chung Shan Medical University Hospital; Taichung Taiwan

9. School of Medicine; Chung Shan Medical University; Taichung Taiwan

10. Department of Otolaryngology; Chung Shan Medical University Hospital; Taichung Taiwan

11. Institute of Medicine, Chung Shan Medical University; Taichung Taiwan

Funder

Ministry of Science and Technology, Taiwan, Grant/Award Number:

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Management, Monitoring, Policy and Law,Toxicology,General Medicine

Reference45 articles.

1. Metastasis from oral cancer: an overview;Noguti;Cancer Genomics Proteomics.,2012

2. Exome sequencing of oral squamous cell carcinoma reveals molecular subgroups and novel therapeutic opportunities;Su;Theranostics.,2017

3. The recurrence and survival of oral squamous cell carcinoma: a report of 275 cases;Wang;Chin J Cancer.,2013

4. Cancer invasion and metastasis;Wittekind;Oncology.,2005

5. Cancer metastasis: mechanisms of inhibition by melatonin;Su;J Pineal Res.,2017

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