Partial penectomy for severe penile ulceration caused by cholesterol crystal embolization

Author:

Matsushima Toshiki1,Mitsunari Kensuke1ORCID,Maekawa Nobuhide1,Yamada Shota1,Ito Hidenori1,Kurata Hiroki1,Nakamura Yuichiro1,Matsuo Tomohiro1,Ohba Kojiro1ORCID,Imamura Ryoichi1

Affiliation:

1. Department of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan

Abstract

IntroductionCholesterol crystal embolism is a rare microembolic disease caused by cholesterol crystals that can present with various symptoms after vascular surgery, catheterization, or anticoagulation therapy. We report a case of penile ulceration caused by cholesterol crystal embolism.Case presentationA 72‐year‐old man undergoing maintenance dialysis for end‐stage renal failure presented with penile pain and a black glans ulcer. Despite low‐density lipoprotein apheresis, he was referred to our hospital because of lack of improvement. Based on his medical history and clinical presentation, including artificial vascular replacement and right toe amputation, cholesterol crystal embolism was suspected and partial penectomy was performed, thus confirming the diagnosis. Penile pain resolved after surgery, and he was discharged on Day 10. Unfortunately, he died after small bowel perforation developed 2 months after surgery.ConclusionPenile ulcers caused by cholesterol crystal embolism may indicate the severity and progression of disease and typically require surgical intervention.

Publisher

Wiley

Subject

Urology

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