Synthetic Approaches to Dimeric and Oligomeric Hexahydropyrrolo[2,3‐b]indole Alkaloids

Author:

Khatua Arindam1,Shyamal Pranay2,Nandy Monosij2,Mondal Debabrata2,Shaw Kundan1,Bisai Alakesh21ORCID

Affiliation:

1. Department of Chemistry IISER Bhopal Bhopal Bypass Road Bhauri, Bhopal, MP 462066 India

2. Department of Chemical Sciences IISER Kolkata Mohanpur, Haringhata, WB 741246 India

Abstract

AbstractNatural product synthesis has been the prime focus for the development of new chemical transformations and the drug discovery. The dimeric and oligomeric hexahydropyrrolo[2,3‐b]indole alkaloids represent a architecturally intriguing class of cyclotryptamine alkaloids. These alkaloids share contiguous stereogenic centers with vicinal all‐carbon quaternary stereogenic centers. Members of this class of alkaloids are reported to show interesting biological activities. Therefore, there are tremendous synthetic interests not only because of their striking architecture but also due to their important biological activities. In this feature article we have discussed the detailed biogenetic hypothesis of these alkaloids and various elegant strategies from different groups, including our contributions in this area. Special emphasis is given for the synthetic approaches to dimeric, trimeric and tetrameric hexahydropyrrolo[2,3‐b]indole alkaloids.

Funder

Science and Engineering Research Board

Publisher

Wiley

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.7亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2025 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3