Investigation of the effect of Low‐Level Laser Therapy on arm lymphedema in breast cancer patients: A noninvasive treatment for an intractable morbidity

Author:

Farhan Farshid1,Samei Mahmood1,Abdshah Alireza23ORCID,Kazemian Ali1,Shahriarian Shahriar4,Amouzegar‐Hashemi Farnaz1,Farzin Mostafa5,Ghalehtaki Reza1,Jafari Fatemeh16,Cuccia Francesco7

Affiliation:

1. Radiation Oncology Research Center (RORC), Cancer Institute Tehran University of Medical Sciences Tehran Iran

2. School of Medicine Tehran University of Medical Sciences Tehran Iran

3. Department of Public Health Sciences Division of Biostatistics, University of Miami Miller School of Medicine Miami Florida USA

4. Department of Radiology, Imam Khomeini Hospital Complex Tehran University of Medical Sciences Tehran Iran

5. Brain and spinal cord injury research center, Neuroscience Institute Tehran University of Medical Sciences Tehran Iran

6. Department of Radiation Oncology, Cancer Institute, Imam Khomeini Hospital Complex Tehran University of Medical Sciences Tehran Iran

7. Advanced Radiation Oncology Department Sacro Cuore Don Calabria Hospital Negrar Veneto Italy

Abstract

AbstractPurposeThis article aims to study the effect of Low‐Level Laser Therapy (LLLT) on arm lymphedema in patients who have breast cancer.Methods and MaterialsTwenty‐three patients were selected in a nonrandomized phase‐2 clinical trial. After measuring the circumference of the affected and unaffected limbs at 6‐points, the volume of the limbs, the degree of mental symptoms on visual analog scale by the patient upon entering the study, and performing an ultrasound on the patient's axilla to locate the fibrotic areas, a low‐level laser device at a therapeutic dose of 2 J/cm2 was used to treat the patients three times a week for 4 weeks, and after an 8‐week gap, for another similar period. Measurement of circumference and volume of affected and unaffected limbs and mental symptoms were carried out at the end of the 4th week, the beginning of the 12th week, and the end of the 16th week, and the obtained results were compared with those before the treatment.ResultsWe noted that the average reductions in the circumference and volume of the affected limb, as compared with the unaffected limb, were about 16% and 21.7%, respectively, and improvement in the patient's mental symptoms was about 32%. Another notable observation was the great enthusiasm of most patients to continue their treatment, particularly from the second cycle onward.ConclusionsLLLT can, at least in association with current standard methods, be used for arm lymphedema to introduce further reductions in pain and volume.

Publisher

Wiley

Subject

General Medicine

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