Targeting mTORC2/HDAC3 Inhibits Stemness of Liver Cancer Cells Against Glutamine Starvation-Reference-Cited by-同舟云学术

Targeting mTORC2/HDAC3 Inhibits Stemness of Liver Cancer Cells Against Glutamine Starvation

Published:2022-02-20 Issue:20 Volume:9 Page:2103887
ISSN:2198-3844
Container-title:Advanced Science
language:en
Short-container-title:Advanced Science

Author:

Zhang Hui‐Lu¹,Chen Ping¹,Yan He‐Xin²,Fu Gong‐Bo³,Luo Fei‐Fei¹,Zhang Jun¹,Zhao Shi‐Min¹,Zhai Bo²,Yu Jiang‐Hong¹,Chen Lin¹,Cui Hao‐Shu¹,Chen Jian¹,Huang Shuai²,Zeng Jun⁴,Xu Wei¹,Wang Hong‐Yang⁵⁶,Liu Jie¹^ORCID

Affiliation:

1. Department of Digestive Diseases of Huashan Hospital and Institutes of Biomedical Sciences Fudan University Shanghai 200040 China

2. Renji Hospital School of Medicine Shanghai Jiaotong University Shanghai 200120 China

3. Department of Medical Oncology Affiliated Jinling Hospital Medical School of Nanjing University Nanjing 210093 China

4. Key Laboratory of Separation Science for Analytical Chemistry Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian 116023 China

5. Eastern Hepatobiliary Surgery Hospital Second Military Medical University Shanghai 200433 China

6. National Center for Liver Cancer Shanghai 200433 China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/advs.202103887

Reference43 articles.

1. Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis

2. Targeting Lactate Dehydrogenase-A Inhibits Tumorigenesis and Tumor Progression in Mouse Models of Lung Cancer and Impacts Tumor-Initiating Cells

3. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

4. Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC

5. Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation

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