1. School of Health Science and Engineering University of Shanghai for Science and Technology Shanghai 200093 P. R. China
2. Department of Orthopaedic Oncology Changzheng Hospital Naval Military Medical University Shanghai 200003 P. R. China
3. Department of Bone Tumor The Affiliated Hospital of Qingdao University No. 59, Haier Road Qingdao Shandong 266000 P. R. China
4. Department of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital Shanghai Jiao Tong University School of Medicine 197 Ruijin 2nd Road Shanghai 200025 P. R. China
5. Pharmaceutical Sciences Laboratory Faculty of Science and Engineering Åbo Akademi University Turku 20520 Finland