Micro‐ and Nanomanufacturing for Biomedical Applications and Nanomedicine: A Perspective

Author:

Wang Fanjin1,Harker Anthony2,Edirisinghe Mohan1,Parhizkar Maryam3ORCID

Affiliation:

1. Department of Mechanical Engineering University College London London WC1E 7JE UK

2. Department of Physics and Astronomy University College London London WC1E 6BT UK

3. School of Pharmacy University College London London WC1N 1AX UK

Abstract

Almost a century's dedicated research into micro‐ and nanomaterials has yielded fruitful development of preparation methods, achieving fine control over product properties among a broad spectrum of materials. One critical application of these materials lies within the healthcare sector for diagnostic, prophylactic, and therapeutic purposes. However, bench‐to‐bedside translations are still hindered by some unmet demands, especially the scaling‐up from lab‐scale preparation to industry‐level production. The current review recapitulates the strategies of micro‐ and nanomaterial preparation from a holistic viewpoint. The similarities in synthesis and processing methods for various types of materials are highlighted. Furthermore, patents of commercialized nanomedicines are revisited to reveal a solid progress of micro‐ and nanomanufacturing in the last decade. In conclusion, further interdisciplinary research between fields in materials manufacturing is beneficial for the clinical translation and eventually unleashing the power of materials at small dimensions.

Funder

Engineering and Physical Sciences Research Council

Publisher

Wiley

Subject

General Earth and Planetary Sciences,General Environmental Science

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