A surface plasmon resonance assay for measurement of neuraminidase inhibition, sensitivity of wild-type influenza neuraminidase and its H274Y mutant to the antiviral drugs zanamivir and oseltamivir

Author:

Somasundaram Balaji12,Fee Conan J.12,Fredericks Rayleen12,Watson Andrew J. A.13,Fairbanks Antony J.13,Hall Richard J.4

Affiliation:

1. Biomolecular Interaction Centre; University of Canterbury; Christchurch New Zealand

2. Chemical and Process Engineering; University of Canterbury; Private Bag 4800 8140 Christchurch Canterbury New Zealand

3. Department of Chemistry; University of Canterbury; Private Bag 4800 8140 Christchurch New Zealand

4. National Centre for Biosecurity and Infectious Disease (NCBID); Institute of Environmental Science and Research (ESR); 66 Ward Street 5018 Upper Hutt New Zealand

Publisher

Wiley

Subject

Molecular Biology,Structural Biology

Reference30 articles.

1. Detection of influenza virus: traditional approaches and development of biosensors;Amano;Anal. Bioanal. Chem.,2005

2. Generation and characterization of a mutant of influenza A virus selected with the neuraminidase inhibitor RWJ-270201;Bantia;Antiviral Res.,2000

3. Chemical probes for drug-resistance assessment by binding competition (RABC): oseltamivir susceptibility evaluation;Cheng;Angew. Chem. Int. Ed.,2013

4. Structural basis for oseltamivir resistance of influenza viruses;Collins;Vaccine,2009

5. Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants;Collins;Nature,2008

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