Is HLA type a possible cancer risk modifier in Lynch syndrome?

Author:

Ahadova Aysel12ORCID,Witt Johannes12,Haupt Saskia34,Gallon Richard5,Hüneburg Robert67,Nattermann Jacob67,ten Broeke Sanne8,Bohaumilitzky Lena12,Hernandez‐Sanchez Alejandro12,Santibanez‐Koref Mauro5,Jackson Michael S.5,Ahtiainen Maarit9,Pylvänäinen Kirsi10,Andini Katarina8,Grolmusz Vince Kornel1112,Möslein Gabriela13,Dominguez‐Valentin Mev14ORCID,Møller Pål14,Fürst Daniel1516,Sijmons Rolf8,Borthwick Gillian M.5,Burn John5,Mecklin Jukka‐Pekka1718,Heuveline Vincent34,von Knebel Doeberitz Magnus12ORCID,Seppälä Toni192021,Kloor Matthias12

Affiliation:

1. Department of Applied Tumor Biology Institute of Pathology, University Hospital Heidelberg Heidelberg Germany

2. Cooperation Unit Applied Tumor Biology German Cancer Research Centre (DKFZ) Heidelberg Germany

3. Engineering Mathematics and Computing Lab (EMCL) Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University Heidelberg Germany

4. Data Mining and Uncertainty Quantification (DMQ) Heidelberg Institute for Theoretical Studies (HITS) Heidelberg Germany

5. Translational and Clinical Research Institute Newcastle University, International Centre for Life Newcastle upon Tyne UK

6. Department of Internal Medicine I University Hospital Bonn Bonn Germany

7. National Center for Hereditary Tumor Syndromes University Hospital Bonn Bonn Germany

8. Department of Genetics University Medical Center Groningen Groningen The Netherlands

9. Department of Pathology Nova Hospital Jyväskylä Finland

10. Department of Education and science Nova Hospital Jyväskylä Finland

11. Department of Molecular Genetics National Institute of Oncology Budapest Hungary

12. Hereditary Cancers Research Group Hungarian Academy of Sciences—Semmelweis University Budapest Hungary

13. Department of Surgery Ev. Krankenhaus Bethesda Hospital Duisburg Germany

14. Department of Tumor Biology Institute of Cancer Research, The Norwegian Radium Hospital Oslo Norway

15. Institute of Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Transfusion Service, Baden Wuerttemberg‐Hessen University Hospital Ulm Ulm Germany

16. Institute of Transfusion Medicine University of Ulm Ulm Germany

17. Faculty of Sport and Health Sciences University of Jyväskylä Jyväskylä Finland

18. Department of Surgery Nova Hospital Jyväskylä Finland

19. Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Center Tampere University Hospital Tampere Finland

20. Department of Gastrointestinal Surgery Helsinki University Central Hospital Helsinki Finland

21. Applied Tumor Genomics Research Program University of Helsinki Helsinki Finland

Funder

Deutsche Forschungsgemeinschaft

Deutsche Krebshilfe

Emil Aaltosen Säätiö

Jane ja Aatos Erkon Säätiö

Suomen Lääketieteen Säätiö

Wilhelm Sander Foundation

Klaus Tschira Stiftung

Publisher

Wiley

Subject

Cancer Research,Oncology

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