ESCA study of new antithrombogenic materials: Surface composition of poly(propylene oxide)‐segmented nylon 610 and its blood compatibility

Abstract

AbstractSurface composition and blood compatibility of a series of segmented polymers based on poly(propylene oxide) (PPO) and nylon 610 were investigated. Electron spectroscopy for chemical analysis (ESCA) measurements revealed that the chemical composition of PPO‐segmented nylon 610 surface is regulated by nylon 610 crystallization, and the PPO enrichment effect on the air‐facing surface was correlated with both the degree of crystallinity of nylon 610 and the nylon 610 crystallite thickness. Platelet adhesion was minimized for the copolymer having a long period of approximately 12 nm and a crystallite thickness of 6,5 nm. This copolymer surface had the same chemical composition as the bulk, indicating that the particular surface microstructure composed of crystalline and amorphous phases could be a determining factor for suppressing platelet adhesion.