A novel estrogen receptor GPER mediates proliferation induced by 17β-estradiol and selective GPER agonist G-1 in estrogen receptor α (ERα)-negative ovarian cancer cells
Author:
Affiliation:
1. Laboratory of Reproductive Endocrinology, Department of Physiology; Harbin Medical University; Harbin 150081 China
2. Department of Obstetrics and Gynecology; The First Affiliated Hospital of Harbin Medical University; Harbin 150001 China
Publisher
Wiley
Subject
Cell Biology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/cbin.10243/fullpdf
Reference32 articles.
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3. Virtual and biomolecular screening converge on a selective agonist for GPR30;Bologa;Nat Chem Biol,2006
4. Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21, and induction of G(2) cell-cycle arrest;Chan;Cell Death Differ,2010
5. Estradiol up-regulates antiapoptotic Bcl-2 messenger ribonucleic acid and protein in tumorigenic ovarian surface epithelium cells;Choi;Endocrinology,2001
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