<scp>BRD4</scp> degradation blocks expression of <scp>MYC</scp> and multiple forms of stem cell resistance in Ph <sup>+</sup> chronic myeloid leukemia-Reference-Cited by-同舟云学术

BRD4 degradation blocks expression of MYC and multiple forms of stem cell resistance in Ph ⁺ chronic myeloid leukemia

Published:2022-07-18 Issue:9 Volume:97 Page:1215-1225
ISSN:0361-8609
Container-title:American Journal of Hematology
language:en
Short-container-title:American J Hematol

Author:

Peter Barbara¹²^ORCID,Eisenwort Gregor¹²^ORCID,Sadovnik Irina¹²^ORCID,Bauer Karin¹²,Willmann Michael¹³,Rülicke Thomas¹⁴^ORCID,Berger Daniela²,Stefanzl Gabriele²,Greiner Georg¹⁵^ORCID,Hoermann Gregor¹⁵⁶^ORCID,Keller Alexandra¹²,Wolf Dominik⁷⁸,Čulen Martin⁹¹⁰^ORCID,Winter Georg E.¹¹^ORCID,Hoffmann Thomas¹²,Schiefer Ana‐Iris¹³^ORCID,Sperr Wolfgang R.¹²^ORCID,Zuber Johannes¹²¹⁴^ORCID,Mayer Jiří⁹¹⁰,Valent Peter¹²^ORCID

Affiliation:

1. Ludwig Boltzmann Institute for Hematology and Oncology Medical University of Vienna Vienna Austria

2. Department of Internal Medicine I, Division of Hematology & Hemostaseology Medical University of Vienna Vienna Austria

3. Department for Companion Animals and Horses, University Clinic for Small Animals, Internal Medicine Small Animals University of Veterinary Medicine Vienna Vienna Austria

4. Institute of Laboratory Animal Science University of Veterinary Medicine Vienna Vienna Austria

5. Department of Laboratory Medicine Medical University of Vienna Vienna Austria

6. MLL Munich Leukemia Laboratory Munich Germany

7. Department of Hematology and Oncology Innsbruck Medical University Innsbruck Austria

8. Department of Hematology, Oncology and Rheumatology, Center of Integrated Oncology Cologne Bonn University Hospital of Bonn Bonn Germany

9. Department of Internal Medicine, Hematology and Oncology, Faculty of Medicine Masaryk University Brno Czech Republic

10. Department of Internal Medicine, Hematology and Oncology University Hospital Brno Brno Czech Republic

11. CeMM‐Research Center for Molecular Medicine of the Austrian Academy of Sciences Vienna Austria

12. Research Institute of Molecular Pathology (IMP) Vienna BioCenter (VBC) Vienna Austria

13. Department of Pathology Medical University of Vienna Vienna Austria

14. Medical University of Vienna Vienna BioCenter (VBC) Vienna Austria

Funder

Austrian Science Fund

Celgene

Publisher

Wiley

Subject

Hematology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajh.26650

Reference54 articles.

1. The molecular biology of chronic myeloid leukemia

2. Signal Transduction Pathways in BCR-ABL Transformed Cells

3. Biology of chronic myelogenous leukemia—signaling pathways of initiation and transformation

4. Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia

5. Hematologic and Cytogenetic Responses to Imatinib Mesylate in Chronic Myelogenous Leukemia

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