Electrospun PCL‐Based Materials for Health‐Care Applications: An Overview

Author:

Mokhena Teboho Clement1,Chabalala Mandla Brian23,Mapukata Sivuyisiwe1,Mtibe Asanda4ORCID,Hlekelele Lerato4,Cele Zamani4,Mochane Mokgaotsa Jonas5,Ntsendwana Bulelwa1,Nhlapo Toitoi Amos6,Mokoena Teboho Patrick7,Bambo Mokae Fanuel1,Matabola Kgabo Phillemon8,Ray Suprakas Sinha2,Sadiku Emmanuel Rotimi9,Shingange Katekani1

Affiliation:

1. Nanotechnology Innovation Centre (NIC) Advanced Materials Division Mintek, Private Bag X3015 Randburg 2125 South Africa

2. Centre of Materials, CSET University of South Africa Johannesburg 1710 South Africa

3. Department of Physics, CSET University of South Africa Johannesburg 1710 South Africa

4. Centre for Nanostructures and Advanced Materials DSI‐CSIR Nanotechnology Innovation Centre Council for Scientific and Industrial Research Pretoria 0001 South Africa

5. Department of Life Sciences Central University of Technology Free State Bloemfontein 9301 South Africa

6. Department of Medical Physics Sefako Makgatho Health Sciences University P. O Box 146 Medunsa 0204 South Africa

7. Department of Physics University of the Free State P. Bag X13 Phuthaditjhaba 9866 South Africa

8. Department of Water and Sanitation University of Limpopo Private Bag X 1106 Sovenga 0727 South Africa

9. Institute of Nano Engineering Research (INER) Department of Chemical Metallurgical and Materials Engineering (Polymer Technology Division) Tshwane University of Technology Pretoria 0183 South Africa

Abstract

AbstractPolycaprolactone (PCL) is one of the durable polymers with potential in a plethora of healthcare applications. Its biological properties, degradability, chemical properties, and mechanical properties can further be modified to manufacture desired products for modern biomedical applications. Electrospinning of PCL offers the opportunity to design treatment materials that resemble human tissues and facilitate regeneration at the target site. The resultant materials can also be modified by loading other active functional materials to broaden their applications. Herein, the recent advances in the preparation and modification of PCL‐based materials for healthcare applications are elucidated. The challenges and future trends for its application in modern biomedical applications are also outlined.

Publisher

Wiley

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Synthesis and Viscoelastic Properties of Polycaprolactone/Polyvinylidene Fluoride/Nanohydroxyapatite Composite Scaffolds;Macromolecular Materials and Engineering;2024-07-03

2. A review of preparation methods and biomedical applications of poly(ε-caprolactone)-based novel formulations;Journal of Materials Science;2024-06

3. Fabrication of PCL/sepiolite composite nanofibers;7th International Scientific Conference Contemporary Trends and Innovations in Textile Industry – CT&ITI 2024 - zbornik radova;2024

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