MR spectroscopy for in vivo assessment of the oncometabolite 2-hydroxyglutarate and its effects on cellular metabolism in human brain gliomas at 9.4T-Reference-Cited by-同舟云学术

MR spectroscopy for in vivo assessment of the oncometabolite 2-hydroxyglutarate and its effects on cellular metabolism in human brain gliomas at 9.4T

Published:2016-03-11 Issue:4 Volume:44 Page:823-833
ISSN:1053-1807
Container-title:Journal of Magnetic Resonance Imaging
language:en
Short-container-title:J. Magn. Reson. Imaging

Author:

Bisdas Sotirios¹²³,Chadzynski Grzegorz L.⁴⁵,Braun Christian³⁶⁷,Schittenhelm Jens³⁷⁸⁹,Skardelly Marco³⁷⁹¹⁰,Hagberg Gisela E.⁴⁵,Ethofer Thomas⁴¹¹,Pohmann Rolf⁵,Shajan G.⁵,Engelmann Jörn⁴⁵,Tabatabai Ghazaleh³⁶⁷⁹¹²,Ziemann Ulf³⁶⁹,Ernemann Ulrike¹³⁹,Scheffler Klaus⁴⁵

Affiliation:

1. Department of Neuroradiology; Eberhard-Karls University Tübingen; Tübingen Germany

2. Department of Neuroradiology; National Hospital for Neurology and Neurosurgery, University College London Hospitals; London UK

3. Center for CNS tumors, Comprehensive Cancer Center Tübingen-Stuttgart, University Hospital Tübingen, Eberhard Karls University Tübingen; Tübingen Germany

4. Department of Biomedical Magnetic Resonance; Eberhard-Karls University Tübingen; Tübingen Germany

5. High-field Magnetic Resonance Center; Max Planck Institute for Biological Cybernetics; Tübingen Germany

6. Department of Neurology & Stroke; Hertie Institute for Clinical Brain Research, Eberhard-Karls University Tübingen; Tübingen Germany

7. Interdisciplinary Division of Neuro-Oncology; University Hospital Tübingen, Hertie Institute for Clinical Brain Research, Eberahrd Karls University; Tübingen Germany

8. Department of Neuropathology; Eberhard-Karls University Tübingen; Tübingen Germany

9. Center for Personalized Medicine; Eberhard Karls University; Tübingen Germany

10. Department of Neurosurgery; Eberhard-Karls University Tübingen; Tübingen Germany

11. Clinic for Psychiatry and Psychotherapy; Eberhard-Karls University Tübingen; Tübingen Germany

12. German Cancer Consortium (DKTK); DKFZ partner site Tübingen; Tübingen Germany

Funder

Fortüne Junior Program (an intramural founding program of the Medical Faculty of Eberhard Karls University Tübingen)

German Research Foundation

Max Planck Society

Ministry of Science, Research and the Arts of Baden-Wuerttemberg

Publisher

Wiley

Subject

Radiology Nuclear Medicine and imaging

Reference47 articles.

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2. Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas;Killela;Oncotarget,2014

3. An integrated genomic analysis of human glioblastoma multiforme;Parsons;Science,2008

4. Comprehensive genomic characterization defines human glioblastoma genes and core pathways;The cancer genome atlas research network;Nature,2008

5. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate;Dang;Nature,2009

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