International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors

Author:

Kuan Edward C.1ORCID,Wang Eric W.2ORCID,Adappa Nithin D.3,Beswick Daniel M.4ORCID,London Nyall R.56,Su Shirley Y.7,Wang Marilene B.4ORCID,Abuzeid Waleed M.8,Alexiev Borislav9,Alt Jeremiah A.10ORCID,Antognoni Paolo11,Alonso‐Basanta Michelle12,Batra Pete S.13,Bhayani Mihir13,Bell Diana14,Bernal‐Sprekelsen Manuel15,Betz Christian S.16,Blay Jean‐Yves17,Bleier Benjamin S.18ORCID,Bonilla‐Velez Juliana8,Callejas Claudio1920ORCID,Carrau Ricardo L.20,Casiano Roy R.21,Castelnuovo Paolo22,Chandra Rakesh K.23,Chatzinakis Vasileios24,Chen Simon B.25,Chiu Alexander G.26,Choby Garret27ORCID,Chowdhury Naweed I.23,Citardi Martin J.28,Cohen Marc A.29,Dagan Roi30,Dalfino Gianluca22ORCID,Dallan Iacopo31,Dassi Camila Soares32,de Almeida John33,Dei Tos Angelo P.34,DelGaudio John M.35,Ebert Charles S.36,El‐Sayed Ivan H.37,Eloy Jean Anderson38ORCID,Evans James J.39,Fang Christina H.40ORCID,Farrell Nyssa F.41ORCID,Ferrari Marco42ORCID,Fischbein Nancy43,Folbe Adam44,Fokkens Wytske J.45,Fox Meha G.46,Lund Valerie J.47,Gallia Gary L.48,Gardner Paul A.49,Geltzeiler Mathew50,Georgalas Christos51ORCID,Getz Anne E.52,Govindaraj Satish53,Gray Stacey T.54,Grayson Jessica W.55ORCID,Gross Bradley A.49,Grube Jordon G.56,Guo Ruifeng57,Ha Patrick K.37,Halderman Ashleigh A.58,Hanna Ehab Y.7,Harvey Richard J.59ORCID,Hernandez Stephen C.60,Holtzman Adam L.61,Hopkins Claire62ORCID,Huang Zhigang63,Huang Zhenxiao63,Humphreys Ian M.8ORCID,Hwang Peter H.64ORCID,Iloreta Alfred M.53,Ishii Masaru5,Ivan Michael E.65,Jafari Aria8ORCID,Kennedy David W.3,Khan Mohemmed53,Kimple Adam J.36ORCID,Kingdom Todd T.52,Knisely Anna66,Kuo Ying‐Ju67,Lal Devyani27ORCID,Lamarre Eric D.68,Lan Ming‐Ying69ORCID,Le Hien70,Lechner Matt71,Lee Nancy Y.72,Lee Jivianne K.73,Lee Victor H.74,Levine Corinna G.21,Lin Jin‐Ching75,Lin Derrick T.54,Lobo Brian C.76,Locke Tran46,Luong Amber U.28ORCID,Magliocca Kelly R.77,Markovic Svetomir N.78,Matnjani Gesa79,McKean Erin L.80,Meço Cem8182ORCID,Mendenhall William M.30,Michel Loren83,Na'ara Shorook37,Nicolai Piero42,Nuss Daniel W.60,Nyquist Gurston G.84,Oakley Gretchen M.10,Omura Kazuhiro85ORCID,Orlandi Richard R.10ORCID,Otori Nobuyoshi85,Papagiannopoulos Peter13,Patel Zara M.64ORCID,Pfister David G.83,Phan Jack86,Psaltis Alkis J.87,Rabinowitz Mindy R.84,Ramanathan Murugappan5,Rimmer Ryan88,Rosen Marc R.84,Sanusi Olabisi89,Sargi Zoukaa B.21,Schafhausen Philippe90,Schlosser Rodney J.91,Sedaghat Ahmad R.92ORCID,Senior Brent A.36ORCID,Shrivastava Raj93,Sindwani Raj68,Smith Timothy L.50ORCID,Smith Kristine A.94ORCID,Snyderman Carl H.1ORCID,Solares C. Arturo35,Sreenath Satyan B.95,Stamm Aldo32,Stölzel Katharina16,Sumer Baran58,Surda Pavol62,Tajudeen Bobby A.13,Thompson Lester D. R.96,Thorp Brian D.36,Tong Charles C. L.3ORCID,Tsang Raymond K.97,Turner Justin H.23,Turri‐Zanoni Mario22,Udager Aaron M.98,van Zele Thibaut99ORCID,VanKoevering Kyle20,Welch Kevin C.100,Wise Sarah K.35,Witterick Ian J.101,Won Tae‐Bin102ORCID,Wong Stephanie N.103,Woodworth Bradford A.55ORCID,Wormald Peter‐John87,Yao William C.28ORCID,Yeh Chien‐Fu69ORCID,Zhou Bing63ORCID,Palmer James N.3

Affiliation:

1. Departments of Otolaryngology–Head and Neck Surgery and Neurological Surgery University of California, Irvine Orange California USA

2. Department of Otolaryngology University of Pittsburgh Medical Center Pittsburgh Pennsylvania USA

3. Department of Otorhinolaryngology–Head and Neck Surgery Perelman School of Medicine, University of Pennsylvania Philadelphia Pennsylvania USA

4. Department of Otolaryngology–Head and Neck Surgery University of California Los Angeles Los Angeles California USA

5. Department of Otolaryngology–Head and Neck Surgery Johns Hopkins University School of Medicine Baltimore Maryland USA

6. Sinonasal and Skull Base Tumor Program Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health Bethesda Maryland USA

7. Department of Head and Neck Surgery The University of Texas MD Anderson Cancer Center Houston Texas USA

8. Department of Otolaryngology–Head and Neck Surgery University of Washington Seattle Washington USA

9. Department of Pathology Northwestern University Feinberg School of Medicine, Northwestern Memorial Hospital Chicago Illinois USA

10. Department of Otolaryngology–Head and Neck Surgery University of Utah Salt Lake City Utah USA

11. Division of Radiation Oncology University of Insubria, ASST Sette Laghi Hospital Varese Italy

12. Department of Radiation Oncology University of Pennsylvania, Perelman School of Medicine Philadelphia Pennsylvania USA

13. Department of Otorhinolaryngology–Head and Neck Surgery Rush University Medical Center Chicago Illinois USA

14. Department of Pathology City of Hope Comprehensive Cancer Center Duarte California USA

15. Otorhinolaryngology Department, Surgery and Medical‐Surgical Specialties Department, Faculty of Medicine and Health Sciences Universitat de Barcelona Barcelona Spain

16. Department of Otorhinolaryngology University Medical Center Hamburg‐Eppendorf Hamburg Germany

17. Department of Medical Oncology Centre Léon Bérard, UNICANCER, Université Claude Bernard Lyon I Lyon France

18. Department of Otolaryngology–Head and Neck Surgery Harvard Medical School Boston Massachusetts USA

19. Department of Otolaryngology Pontificia Universidad Católica de Chile Santiago Chile

20. Department of Otolaryngology–Head and Neck Surgery The Ohio State University Columbus Ohio USA

21. Department of Otolaryngology–Head and Neck Surgery University of Miami Miller School of Medicine Miami Florida USA

22. Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences University of Insubria, ASST Sette Laghi Hospital Varese Italy

23. Department of Otolaryngology–Head and Neck Surgery Vanderbilt University Medical Center Nashville Tennessee USA

24. Department of Head, Neck and Skull Base Surgery Hygeia Hospital Athens Greece

25. Department of Pathology Stanford University Stanford California USA

26. Department of Otolaryngology–Head and Neck Surgery University of Kansas Medical Center Kansas City Kansas USA

27. Department of Otolaryngology–Head and Neck Surgery Mayo Clinic Rochester Minnesota USA

28. Department of Otorhinolaryngology‐Head & Neck Surgery, McGovern Medical School The University of Texas Health Science Center at Houston Houston Texas USA

29. Department of Surgery, Head and Neck Service Memorial Sloan Kettering Cancer Center New York New York USA

30. Department of Radiation Oncology University of Florida College of Medicine Jacksonville Florida USA

31. Department of Otolaryngology–Head and Neck Surgery Pisa University Hospital Pisa Italy

32. São Paulo ENT Center (COF) Edmundo Vasconcelos Complex São Paulo Brazil

33. Department of Otolaryngology–Head and Neck Surgery University Health Network, University of Toronto Toronto Ontario Canada

34. Section of Pathology, Department of Medicine University of Padua Padua Italy

35. Department of Otolaryngology–Head and Neck Surgery Emory University School of Medicine Atlanta Georgia USA

36. Department of Otolaryngology–Head and Neck Surgery University of North Carolina at Chapel Hill Chapel Hill North Carolina USA

37. Department of Otolaryngology–Head and Neck Surgery University of California San Francisco California USA

38. Department of Otolaryngology–Head and Neck Surgery Rutgers New Jersey Medical School Newark New Jersey USA

39. Department of Neurological Surgery and Otolaryngology–Head and Neck Surgery Thomas Jefferson University Philadelphia Pennsylvania USA

40. Department of Otorhinolaryngology–Head and Neck Surgery, Montefiore Medical Center The University Hospital for Albert Einstein College of Medicine Bronx New York USA

41. Department of Otolaryngology–Head and Neck Surgery Washington University in St. Louis St. Louis Missouri USA

42. Section of Otorhinolaryngology–Head and Neck Surgery, Department of Neurosciences University of Padua Padua Italy

43. Department of Radiology Stanford University Stanford California USA

44. Department of Otolaryngology–Head and Neck Surgery Oakland University William Beaumont School of Medicine Royal Oak Michigan USA

45. Department of Otorhinolaryngology Amsterdam UMC Amsterdam The Netherlands

46. Department of Otolaryngology–Head and Neck Surgery Baylor College of Medicine Houston Texas USA

47. Ear Institute University College London London UK

48. Department of Neurosurgery Johns Hopkins University School of Medicine Baltimore Maryland USA

49. Department of Neurological Surgery University of Pittsburgh Medical Center Pittsburgh Pennsylvania USA

50. Department of Otolaryngology–Head and Neck Surgery Oregon Health and Science University Portland Oregon USA

51. Department of Otorhinolaryngology–Head and Neck Surgery University of Nicosia Medical School Nicosia Cyprus

52. Department of Otolaryngology–Head and Neck Surgery University of Colorado Aurora Colorado USA

53. Department of Otolaryngology–Head and Neck Surgery Icahn School of Medicine at Mount Sinai New York New York USA

54. Department of Otolaryngology–Head and Neck Surgery Massachusetts Eye and Ear Infirmary Boston Massachusetts USA

55. Department of Otolaryngology–Head and Neck Surgery University of Alabama at Birmingham Birmingham Alabama USA

56. Department of Otolaryngology–Head and Neck Surgery Albany Medical Center Albany New York USA

57. Department of Laboratory Medicine and Pathology Mayo Clinic Rochester Minnesota USA

58. Department of Otolaryngology–Head and Neck Surgery The University of Texas Southwestern Medical Center Dallas Texas USA

59. Rhinology and Skull Base Research Group, Applied Medical Research Centre University of South Wales Sydney New South Wales Australia

60. Department of Otolaryngology–Head and Neck Surgery LSU Health Sciences Center New Orleans Louisiana USA

61. Department of Radiation Oncology Mayo Clinic Florida Jacksonville Florida USA

62. Department of Otolaryngology–Head and Neck Surgery Guys and St Thomas’ Hospital London UK

63. Department of Otolaryngology–Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otolaryngology–Head and Neck Surgery Ministry of Education Beijing China

64. Department of Otolaryngology–Head and Neck Surgery Stanford University School of Medicine Stanford California USA

65. Department of Neurological Surgery University of Miami Miller School of Medicine Miami Florida USA

66. Department of Otolaryngology, Head and Neck Surgery Swedish Medical Center Seattle Washington USA

67. Department of Pathology Taipei Veterans General Hospital Taipei Taiwan

68. Head and Neck Institute, Cleveland Clinic Lerner College of Medicine Cleveland Clinic Cleveland Ohio USA

69. Department of Otorhinolaryngology–Head and Neck Surgery Taipei Veterans General Hospital Taipei Taiwan

70. Department of Radiation Oncology Royal Adelaide Hospital Adelaide South Australia Australia

71. UCL Division of Surgery and Interventional Science and UCL Cancer Institute University College London London UK

72. Department of Radiation Oncology Memorial Sloan Kettering Cancer Center New York New York USA

73. Department of Head and Neck Surgery University of California, Los Angeles David Geffen School of Medicine Los Angeles California USA

74. Department of Clinical Oncology, School of Clinical Medicine, LKS Faculty of Medicine The University of Hong Kong Hong Kong SAR China

75. Department of Radiation Oncology Changhua Christian Hospital Changhua Taiwan

76. Department of Otolaryngology–Head and Neck Surgery University of Florida Gainesville Florida USA

77. Department of Pathology and Laboratory Medicine Emory University School of Medicine Atlanta Georgia USA

78. Division of Medical Oncology, Department of Oncology Mayo Clinic Rochester Minnesota USA

79. Department of Radiation Oncology University Medical Center Hamburg‐Eppendorf Hamburg Germany

80. Department of Otolaryngology–Head and Neck Surgery University of Michigan Ann Arbor Michigan USA

81. Department of Otorhinolaryngology, Head and Neck Surgery Ankara University Medical School Ankara Turkey

82. Department of Otorhinolaryngology Head and Neck Surgery Salzburg Paracelsus Medical University Salzburg Austria

83. Department of Medicine Memorial Sloan Kettering Cancer Center New York New York USA

84. Department of Otolaryngology–Head and Neck Surgery Thomas Jefferson University Philadelphia Pennsylvania USA

85. Department of Otorhinolaryngology The Jikei University School of Medicine Tokyo Japan

86. Department of Radiation Oncology The University of Texas MD Anderson Cancer Center Houston Texas USA

87. Department of Otolaryngology–Head and Neck Surgery Queen Elizabeth Hospital Adelaide South Australia Australia

88. Department of Otolaryngology–Head and Neck Surgery Yale University New Haven Connecticut USA

89. Department of Neurosurgery Oregon Health and Science University Portland Oregon USA

90. Department of Hematology and Oncology University Medical Center Hamburg‐Eppendorf Hamburg Germany

91. Department of Otolaryngology–Head and Neck Surgery Medical University of South Carolina Charleston South Carolina USA

92. Department of Otolaryngology–Head and Neck Surgery University of Cincinnati College of Medicine Cincinnati Ohio USA

93. Department of Neurosurgery and Otolaryngology–Head and Neck Surgery Icahn School of Medicine at Mount Sinai New York New York USA

94. Department of Otolaryngology–Head and Neck Surgery University of Manitoba Winnipeg Manitoba Canada

95. Department of Otolaryngology–Head and Neck Surgery Indiana University Indianapolis Indiana USA

96. Head and Neck Pathology Consultations Woodland Hills California USA

97. Department of Otolaryngology–Head and Neck Surgery, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore

98. Department of Pathology, Michigan Center for Translational Pathology, Rogel Cancer Center University of Michigan Ann Arbor Michigan USA

99. Department of Otorhinolaryngology Ghent University Hospital Ghent Belgium

100. Department of Otolaryngology–Head and Neck Surgery Northwestern University Feinberg School of Medicine Chicago Illinois USA

101. Department of Otolaryngology–Head and Neck Surgery University of Toronto Toronto Ontario Canada

102. Department of Otorhinolaryngology–Head and Neck Surgery Seoul National University Hospital, Seoul National University College of Medicine Seoul South Korea

103. Division of Otorhinolaryngology, Department of Surgery, School of Clinical Medicine, LKS Faculty of Medicine The University of Hong Kong Hong Kong SAR China

Abstract

AbstractBackgroundSinonasal neoplasms, whether benign and malignant, pose a significant challenge to clinicians and represent a model area for multidisciplinary collaboration in order to optimize patient care. The International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors (ICSNT) aims to summarize the best available evidence and presents 48 thematic and histopathology‐based topics spanning the field.MethodsIn accordance with prior International Consensus Statement on Allergy and Rhinology documents, ICSNT assigned each topic as an Evidence‐Based Review with Recommendations, Evidence‐Based Review, and Literature Review based on the level of evidence. An international group of multidisciplinary author teams were assembled for the topic reviews using the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses format, and completed sections underwent a thorough and iterative consensus‐building process. The final document underwent rigorous synthesis and review prior to publication.ResultsThe ICSNT document consists of four major sections: general principles, benign neoplasms and lesions, malignant neoplasms, and quality of life and surveillance. It covers 48 conceptual and/or histopathology‐based topics relevant to sinonasal neoplasms and masses. Topics with a high level of evidence provided specific recommendations, while other areas summarized the current state of evidence. A final section highlights research opportunities and future directions, contributing to advancing knowledge and community intervention.ConclusionAs an embodiment of the multidisciplinary and collaborative model of care in sinonasal neoplasms and masses, ICSNT was designed as a comprehensive, international, and multidisciplinary collaborative endeavor. Its primary objective is to summarize the existing evidence in the field of sinonasal neoplasms and masses.

Publisher

Wiley

Subject

Otorhinolaryngology,Immunology and Allergy

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