Dysregulated hepatic bile acids collaboratively promote liver carcinogenesis

Author:

Xie Guoxiang12,Wang Xiaoning34,Huang Fengjie1,Zhao Aihua1,Chen Wenlian2,Yan Jingyu3,Zhang Yunjing1,Lei Sha1,Ge Kun1,Zheng Xiaojiao1,Liu Jiajian1,Su Mingming2,Liu Ping34,Jia Wei12

Affiliation:

1. Shanghai Key Laboratory of Diabetes Mellitus and Center for Translational Medicine; Shanghai Jiao Tong University Affiliated Sixth People's Hospital; Shanghai China

2. Metabolomics Shared Resource; University of Hawaii Cancer Center; Honolulu HI

3. E-Institute of Shanghai Municipal Education Committee; Shanghai University of Traditional Chinese Medicine; Shanghai China

4. Key Laboratory of Liver and Kidney Diseases (Ministry of Education); Institute of Liver Diseases, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine; Shanghai China

Funder

National Institutes of Health Grant

the State Key Development Programs (973) of Basic Research of China

International Science & Technology Cooperation Program of China

National Natural Science Foundation of China

the Natural Science Foundation of Shanghai, China

the Program for Budgeted Scientific Research Project of Shanghai Municipal Education Commission, China

E-institutes of Shanghai Municipal Education Commission, China

NCI

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference49 articles.

1. GLOBOCAN 2012 http://globocan.iarc.fr/Pages/fact_sheets_cancer.aspx

2. Cancer statistics, 2014;Siegel;CA Cancer J Clin,2014

3. American Cancer Society Liver Cancer Atlanta American Cancer Society http://www.cancer.org/acs/groups/cid/documents/webcontent/003114-pdf.pdf

4. Bile acids activate YAP to promote liver carcinogenesis;Anakk;Cell Rep,2013

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