2022 American College of Rheumatology Guideline for Exercise, Rehabilitation, Diet, and Additional Integrative Interventions for Rheumatoid Arthritis

Author:

England Bryant R.1ORCID,Smith Benjamin J.2ORCID,Baker Nancy A.3ORCID,Barton Jennifer L.4ORCID,Oatis Carol A.5ORCID,Guyatt Gordon6,Anandarajah Allen7ORCID,Carandang Kristine8ORCID,Chan Karmela Kim9ORCID,Constien Deb10,Davidson Eileen11,Dodge Carole V.12,Bemis‐Dougherty Anita13,Everett Sotiria14ORCID,Fisher Nadine15,Fraenkel Liana16ORCID,Goodman Susan M.9ORCID,Lewis Janet17,Menzies Victoria18ORCID,Moreland Larry W.19,Navarro‐Millan Iris20ORCID,Patterson Sarah21ORCID,Phillips Lawrence “Rick”22,Shah Neha23,Singh Namrata24,White Daniel25ORCID,AlHeresh Rawan26ORCID,Barbour Kamil E.27ORCID,Bye Thomas25,Guglielmo Dana28,Haberman Rebecca29ORCID,Johnson Tate1ORCID,Kleiner Anatole7,Lane Chris Y.30ORCID,Li Linda C.31ORCID,Master Hiral32ORCID,Pinto Daniel33,Poole Janet L.34,Steinbarger Kimberly35ORCID,Sztubinski Daniel36,Thoma Louise30ORCID,Tsaltskan Vlad37ORCID,Turgunbaev Marat38,Wells Courtney39ORCID,Turner Amy S.38ORCID,Treadwell Jonathan R.36

Affiliation:

1. University of Nebraska Medical Center and VA Nebraska‐Western Iowa Health Care System Omaha

2. Florida State University Tallahassee

3. Tufts University Boston Massachusetts

4. VA Portland Health Care System and Oregon Health & Science University Portland Oregon

5. Arcadia University Glenside Pennsylvania

6. McMaster University Hamilton Ontario Canada

7. University of Rochester Medical Center Rochester New York

8. San Diego California

9. Hospital for Special Surgery New York

10. Sun Prairie Wisconsin

11. Burnaby British Columbia Canada

12. University of Michigan Hospital and Health System Ann Arbor

13. American Physical Therapy Association Alexandria Virginia

14. Department of Family, Population, Preventive Medicine Stony Brook Renaissance School of Medicine Stony Brook New York

15. University of Buffalo Buffalo New York

16. Yale School of Medicine New Haven Connecticut

17. University of Virginia Charlottesville Virginia

18. University of Florida Gainesville

19. University of Colorado Anschutz Medical Campus Aurora

20. Weill Cornell Medicine New York

21. UCSF Osher Center for Integrative Medicine San Francisco California

22. Noblesville Indiana

23. Stanford Health Care Palo Alto California

24. University of Washington Seattle

25. University of Delaware Newark

26. MGH Institute of Health Professions Boston Massachusetts

27. Centers for Disease Control and Prevention Atlanta Georgia

28. Research Consultant Los Angeles California

29. NYU Langone Health New York

30. University of North Carolina at Chapel Hill

31. University of British Columbia and Arthritis Research Canada, Vancouver British Columbia Canada

32. Vanderbilt University Medical Center, VICTR Nashville Tennesee

33. Marquette University Milwaukee Wisconsin

34. University of New Mexico Albuquerque

35. Husson University Bangor Maine

36. ECRI Institute, Plymouth Meeting Pennsylvania

37. University of California San Diego

38. American College of Rheumatology Atlanta Georgia

39. University of Wisconsin River Falls

Abstract

ObjectiveTo develop initial American College of Rheumatology (ACR) guidelines on the use of exercise, rehabilitation, diet, and additional interventions in conjunction with disease‐modifying antirheumatic drugs (DMARDs) as part of an integrative management approach for people with rheumatoid arthritis (RA).MethodsAn interprofessional guideline development group constructed clinically relevant Population, Intervention, Comparator, and Outcome (PICO) questions. A literature review team then completed a systematic literature review and applied the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to rate the certainty of evidence. An interprofessional Voting Panel (n = 20 participants) that included 3 individuals with RA achieved consensus on the direction (for or against) and strength (strong or conditional) of recommendations.ResultsThe Voting Panel achieved consensus on 28 recommendations for the use of integrative interventions in conjunction with DMARDs for the management of RA. Consistent engagement in exercise received a strong recommendation. Of 27 conditional recommendations, 4 pertained to exercise, 13 to rehabilitation, 3 to diet, and 7 to additional integrative interventions. These recommendations are specific to RA management, recognizing that other medical indications and general health benefits may exist for many of these interventions.ConclusionThis guideline provides initial ACR recommendations on integrative interventions for the management of RA to accompany DMARD treatments. The broad range of interventions included in these recommendations illustrates the importance of an interprofessional, team‐based approach to RA management. The conditional nature of most recommendations requires clinicians to engage persons with RA in shared decision‐making when applying these recommendations.

Funder

ACR

Publisher

Wiley

Subject

Rheumatology

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