Nandrolone and estradiol biomarkers identification in bovine urine applying a liquid chromatography high‐resolution mass spectrometry metabolomics approach

Author:

Ouzia Saadia1,Royer Anne‐Lise1,Pezzolato Marzia2,Benedetto Alessandro2,Biasibetti Elena2,Guitton Yann1,Le Bizec Bruno1,Bozetta Elena2,Dervilly Gaud1ORCID

Affiliation:

1. Oniris, INRAE LABERCA Nantes France

2. Centro di Referenza Nazionale Indagini Biologiche Anabolizzanti Animali ‐ CIBA Experimental Zooprophylactic Institute of Piedmont, Liguria and Valle d'Aosta Torino Italy

Publisher

Wiley

Subject

Spectroscopy,Pharmaceutical Science,Environmental Chemistry,Analytical Chemistry

Reference46 articles.

1. Council Directive 88/146/EEC.Prohibiting the use livestock farming of certain substances having a hormonal action.1988(16):16‐18.

2. European Parliament and Council.REGULATION (EU) 2017/625 on official controls and other official activities performed to ensure the application of food and feed law rules on animal health and welfare plant health and plant protection products amending Regulations (EC) No 999/2001 (EC) No 396/2005 (EC) No 1069/2009 (EC) No 1107/2009 (EU) No 1151/2012 (EU) No 652/2014 (EU) 2016/429 and (EU) 2016/2031 of the European Parliament and of the Council Council Regulations (EC) No 1/2005 and (EC) No 1099/2009 and Council Directives 98/58/EC 1999/74/EC 2007/43/EC 2008/119/EC and 2008/120/EC and repealing Regulations (EC) No 854/2004 and (EC) No 882/2004 of the European Parliament and of the Council Council Directives 89/608/EEC 89/662/EEC 90/425/EEC 91/496/EEC 96/23/EC 96/93/EC and 97/78/EC and Council Decision 92/438/EEC (Official Controls Regulation). In. OJ L 95 7 4 2017 pp.1‐142.

3. Council Directive 96/22/EC.Council Directive 96/22/EC of 29 April 1996 concerning the prohibition on the use in stockfarming of certain substances having a hormonal or thyrostatic action and of beta‐agonists and repealing Directives 81/602/EEC 88/146/EEC and 88/299/EEC.1996.

4. Past, present and future of mass spectrometry in the analysis of residues of banned substances in meat-producing animals

5. 5α-Estrane-3β,17β-diol and 5β-estrane-3α,17β-diol: Definitive screening biomarkers to sign nandrolone abuse in cattle?

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