Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol‐Induced Liver Damage

Author:

Koelmel Jeremy P.12,Tan Wan Y.13,Li Yang2,Bowden John A.45,Ahmadireskety Atiye4,Patt Andrew C.6,Orlicky David J.7,Mathé Ewy6,Kroeger Nicholas M.8,Thompson David C.9,Cochran Jason A.28,Golla Jaya Prakash1ORCID,Kandyliari Aikaterini110ORCID,Chen Ying1,Charkoftaki Georgia1,Guingab‐Cagmat Joy D.2,Tsugawa Hiroshi111213ORCID,Arora Anmol114ORCID,Veselkov Kirill15,Kato Shunji16,Otoki Yurika16,Nakagawa Kiyotaka16,Yost Richard A.24,Garrett Timothy J.24,Vasiliou Vasilis1

Affiliation:

1. Department of Environmental Health Sciences Yale School of Public Health New Haven CT USA

2. Department of Pathology, Immunology and Laboratory Medicine University of Florida Gainesville FL USA

3. Internal Medicine Residency Program Department of Internal Medicine Norwalk Hospital Norwalk CT USA

4. Department of Chemistry University of Florida Gainesville FL USA

5. Center for Environmental and Human Toxicology and Department of Physiological Sciences University of Florida Gainesville FL USA

6. Division of Preclinical Innovation National Center for Advancing Translational SciencesNational Institutes of Health Rockville MD USA

7. Department of Pathology University of Colorado School of Medicine Denver CO USA

8. Computer and Information Science and Engineering University of Florida Gainesville FL USA

9. Department of Clinical Pharmacy University of Colorado Skaggs School of Pharmacy and Pharmaceutical SciencesUniversity of Colorado Aurora CO USA

10. Unit of Human Nutrition Department of Food Science and Human Nutrition Agricultural University of Athens Athens Greece

11. RIKEN Center for Sustainable Resource Science Kanagawa Japan

12. RIKEN Center for Integrative Medical Sciences Kanagawa Japan

13. Department of Biotechnology and Life Science Tokyo University of Agriculture and Technology Tokyo Japan

14. School of Clinical Medicine University of Cambridge Cambridge United Kingdom

15. Department of Metabolism, Digestion and Reproduction Imperial College London United Kingdom

16. Food and Biodynamic Chemistry Laboratory, Graduate School of Agricultural Science Tohoku University Sendai Japan

Funder

National Institute on Alcohol Abuse and Alcoholism

Publisher

Wiley

Subject

Hepatology

Reference41 articles.

1. The hepatic lipidome: From basic science to clinical translation

2. Lipid Metabolism and Liver Inflammation. II. Fatty liver disease and fatty acid oxidation

3. World Health Organization.Global status report on alcohol and health 2018.https://www.who.int/publications‐detail‐redirect/9789241565639. Published September 27 2018. Accessed May 2021.

4. Liver cirrhosis

5. Prevalence of 12-Month Alcohol Use, High-Risk Drinking, and DSM-IV Alcohol Use Disorder in the United States, 2001-2002 to 2012-2013

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