Recombinant botulinum neurotoxin serotype A1 in vivo characterization
Author:
Affiliation:
1. Ipsen Innovation Les Ulis France
2. Neurofit SAS Illkirch France
3. CARPACCIO.cloud Lyon France
4. Univ Lyon, Université Lyon 1, INSERM Stem Cell and Brain Research Institute U1208 Bron France
5. Ipsen Bioinnovation Abingdon UK
Funder
Ipsen
Publisher
Wiley
Subject
General Pharmacology, Toxicology and Pharmaceutics,Neurology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.857
Reference37 articles.
1. Preclinical update on BOTOX® (botulinum toxin type A)-purified neurotoxin complex relative to other botulinurn neurotoxin preparations
2. A comparison of the safety margins of botulinum neurotoxin serotypes A, B, and F in mice
3. The rat Digit Abduction Score (DAS) assay: A physiological model for assessing botulinum neurotoxin-induced skeletal muscle paralysis
4. Optimization of the rat digit abduction score (DAS) assay: Evaluation of botulinum neurotoxin activity in the gastrocnemius lateralis, peronei, and extensor digitorum longus
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