Hydrogels in Biomedical Applications

Abstract

AbstractThe nature of hydrogel polymers is described together with the range of biomedical applications in which their use has been suggested or described in the literature. The field of contact lens materials has provided the greatest variety of synthetic hydrogels and the material requirements for extended wear lenses present problems that are typical of those encountered in biomedical applications in general. The patient literature relating to contact lenses is reviewed and the development of the composition of hydrogel materials is thereby traced and compared with the range of lens materials currently available. In contrast the most commonly encountered, in fact almost the sole, hydrogel material in the literature relating to those areas more conventionally regarded as biomedical, is poly(2‐hydroxeythyl methacrylate) or polyHEMA. The use of this and related hydrogels in various applications including prostheses, ocular surgery, sature coatings, artificial internal organs and drug delivery systems is reviewed.