Off‐target assessment of CRISPR ‐ C as9 guiding RNA s in human i PS and mouse ES cells
Author:
Affiliation:
1. Wellcome Trust Sanger InstituteHinxton Cambridge United Kingdom
Funder
Wellcome Trust
Cancer Research UK
Publisher
Wiley
Subject
Cell Biology,Endocrinology,Genetics
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/dvg.22835
Reference36 articles.
1. Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
2. Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair
3. Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease
4. Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases
5. Multiplex Genome Engineering Using CRISPR/Cas Systems
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