Comparative analysis of excretion of six major compounds of Polygonum orientale L . extract in urine, feces and bile under physiological and myocardial ischemia conditions in rats using UPLC

Comparative analysis of excretion of six major compounds of Polygonum orientale L . extract in urine, feces and bile under physiological and myocardial ischemia conditions in rats using UPLC–MS/MS

Published:2021-05-24 Issue:10 Volume:35 Page:
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomedical Chromatography

Author:

Lu Yuan¹,Li Na¹²^ORCID,Zhu Xiaoqin¹²,Pan Jie³,Wang Yonglin¹,Lan Yanyu³,Li Yongjun³,Wang Aimin³,Sun Jia¹,Liu Chunhua³

Affiliation:

1. State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics Guizhou Medical University Guiyang China

2. School of Pharmacy Guizhou Medical University Guiyang China

3. Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education) Guizhou Medical University Guiyang China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bmc.5174

Reference33 articles.

1. Analysis of metabolites of protocatechuic acid in rats in vivo;Chen J. Q.;Chinese Traditional Patent Medicine,2017

2. UPLC–Q‐TOF–MS/MS analysis on prototypes components and metabolites of effective fractions of Polygonum orientate flower in rat serum and urine;Chen S. Y.;China Journal of Chinese Materia Medica,2019

3. Investigation of the Association Between the Fecal Microbiota and Breast Cancer in Postmenopausal Women: a Population-Based Case-Control Pilot Study

4. Study on the pharmacokinetic effects of disease and compatibility on ginsenosides in rats;Gong X. H.;Chinese Journal of Modern Applied Pharmacy,2019

5. Anti-rheumatoid arthritis effects in adjuvant-induced arthritis in rats and molecular docking studies of Polygonum orientale L. extracts

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