Clonidine, an alpha-2 adrenoceptor agonist relieves mechanical allodynia in oxaliplatin-induced neuropathic mice; potentiation by spinal p38 MAPK inhibition without motor dysfunction and hypotension

Author:

Yeo Ji-Hee1,Yoon Seo-Yeon23,Kim Sol-Ji1,Oh Seog-Bae23,Lee Jang-Hern4,Beitz Alvin J.5,Roh Dae-Hyun1

Affiliation:

1. Department of Oral Physiology and Research Center for Tooth and Periodontal Tissue Regeneration; School of Dentistry, Kyung Hee University; Seoul Republic of Korea

2. Pain Cognitive Function Research Center, Department of Brain and Cognitive Sciences College of Natural Sciences, Seoul National University; Seoul Republic of Korea

3. Department of Neurobiology and Physiology; Dental Research Institute, School of Dentistry, Seoul National University; Seoul Republic of Korea

4. Department of Veterinary Physiology; College of Veterinary Medicine, Seoul National University; Seoul Republic of Korea

5. Department of Veterinary and Biomedical Sciences; College of Veterinary Medicine, University of Minnesota; St Paul MN

Funder

The National Research Foundation of Korea (NRF), the Korea government (MSIP)

Publisher

Wiley

Subject

Cancer Research,Oncology

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